Codonopsis pilosula polysaccharide pill

A technology of codonopsis polysaccharides and sugar dripping pills, which is applied in the direction of pill delivery, medical preparations of non-active ingredients, plant raw materials, etc., to achieve high bioavailability, easy to carry and take, and increase stability

Inactive Publication Date: 2010-05-12
SHANXI MEDICAL UNIV
View PDF1 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problem that existing Codonopsis polysaccharide tablets, oral liquids, injections and other dosage forms have different shortcomings in clinical application, the present invention provides a Codonopsis polysaccharide dripping pill

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] A Codonopsis polysaccharide dripping pill, which is made of Codonopsis polysaccharide as the active ingredient of Codonopsis pilosula and a matrix as an auxiliary material, the weight ratio of Codonopsis polysaccharide to the matrix is ​​1:8, and the matrix is ​​polyethylene glycol 6000;

[0012] The preparation method of Dangshen polysaccharide dripping pills is as follows: mix the Dangshen polysaccharide and the matrix according to the above ratio evenly, heat and melt in a water bath at a temperature of 70°C, drop it into the simethicone condensing agent at a rate of 20 drops per minute, and then cool to 10°C, shape, remove the condensing agent, and make the Codonopsis polysaccharide dripping pills.

Embodiment 2

[0014] A Codonopsis polysaccharide dripping pill, which is made of Codonopsis polysaccharide as the active ingredient of Codonopsis pilosula and a matrix as an auxiliary material, the weight ratio of Codonopsis polysaccharide to the matrix is ​​1:1, and the matrix is ​​polyethylene glycol 4000;

[0015] The preparation method of Codonopsis polysaccharide dripping pills is as follows: mix Codonopsis polysaccharide and matrix evenly according to the above ratio, heat and melt in a water bath at a temperature of 100 ° C, drop into liquid paraffin condensing agent at a rate of 60 drops per minute, and then cool to 15 ℃, forming, removing the condensing agent, that is, making Codonopsis polysaccharide dripping pills.

Embodiment 3

[0017] A Codonopsis polysaccharide dripping pill, made of Codonopsis polysaccharide as the active ingredient of Codonopsis pilosula and a matrix as an auxiliary material, the weight ratio of Codonopsis polysaccharide to the matrix is ​​1:3, and the matrix is ​​stearic acid;

[0018] The preparation method of Dangshen polysaccharide drop pills is as follows: mix the Dangshen polysaccharide and the matrix according to the above ratio evenly, after heating and melting in a water bath at a temperature of 80°C, drop it into the vegetable oil condensing agent at a rate of 40 drops per minute, and then cool to 12°C , forming, and removing the condensing agent, that is, making Codonopsis polysaccharide dripping pills.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a traditional Chinese medicine preparation, in particular to a codonopsis pilosula polysaccharide pill. The invention solves the problems of different disadvantages on clinical application of the current codonopsis pilosula polysaccharide preparation adopting tablets, oral liquid, parenteral soluation. The codonopsis pilosula polysaccharide pill comprises codonopsis pilosula polysaccharide and base material, wherein the weight ratio of the codonopsis pilosula polysaccharide to the base materials is 1:1 to 1:8, and the base material is any one of polyethyleneglycol 6000, polyethyleneglycol 4000, stearic acid, sodium stearate, glycerogelatin, polyoxyethylene monostearate and glycerin monostearate. The preparation method comprises the following steps: mixing the codonopsis pilosula polysaccharide and the base material in proportion; heating and melting the codonopsis pilosula polysaccharide and the base material in water bath with the temperature of 70 to 100 DEG C, and then dipping the mixture into condensing agent at the speed of 20 to 60 drops per minute; cooling the temperature to 10 to 15 DEG C, and forming; and removing the condensing agent. The traditional Chinese medicine preparation has the advantages of clean and bright appearance, beauty, portability, easy taking, quick deconcentration and good absorption in oral cavity and stomach, high bioavailability, stable preparation, few side effect, insurance of the quality of the medicine, high stability, quickness, high efficiency and controlled release.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a Codonopsis polysaccharide dripping pill with immune regulation, anti-tumor and anti-aging effects. Background technique [0002] Chinese herbal medicine Codonopsis Codonopsis is a traditional Chinese medicine, which is the first choice for invigorating the middle and Qi, invigorating the spleen and lungs, strengthening the body, strengthening the body and anti-aging. It is suitable for spleen and lung qi deficiency. The composition of traditional Chinese medicine is complex, and pharmacological experiments show that Codonopsis polysaccharide is the active part of the effective part of Codonopsis pilosula, which has the following effects, 1. Immunomodulatory effect: Codonopsis polysaccharide can improve the macrophage function of macrophages inhibited by cyclophosphamide and hydrocortisone 2. Anti-tumor effect: After inoculating mice with S180 sarcoma cells, differen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/20A61K31/715A61K36/344A61K47/42A61K47/34A61K47/14A61K47/12A61P37/02A61P35/00A61P39/06A61K47/10
Inventor 高建平杨静刘恩荔杨飞苏强
Owner SHANXI MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap