Multiphoton skin lens image automatic analytical system and method for diagnosing malignant melanoma by using same system

Abstract

The invention provides a multiphoton skin lens image automatic analytical system and a method for diagnosing malignant melanoma by using same system. Wherein the image automatic analysis system is composed of a multiphoton skin lens imaging device (1) and an image analytical device (2) which are connected, the multiphoton skin lens imaging device has the following structure: a multiphoton or a laser LED (4) of a multi-light-path synchronous control (10), a skin lens optical lens (5) of an auto zoom and an area array CCD or CMOS system (8) of a Bluetooth dongle (13); wherein a charging port (6) is arranged at one side of the automatic analytical system, the charging port (6) and a lithium battery (7) are connected and are connected with a switch (9); the image analytical device has the following structure: a data collection control assembly, an image preprocessing assembly (15) and a microcomputer (16) of an automatic analysis software package are provided; the microcomputer (16) is connected with the area array CCD or CMOS system (8) through a data line or a Bluetooth dongle.

Description

technical field [0001] The invention belongs to the field of medical equipment, and relates to an automatic multiphoton dermoscopic image analysis system and a non-invasive early rapid diagnosis instrument and method applied to skin malignant melanoma. technical background [0002] Melanocytic Tumor (Melanocytic Tumor MT) is composed of benign and malignant melanocytic tumors; at present, researchers pay most attention to malignant melanocytic tumors, referred to as: malignant melanoma or malignant melanoma (Malignant Melanoma MM). Occurring in the skin, it is one of the first fatal diseases of the skin with high malignancy, easy transfer, and high risk; in recent years, the incidence of MM in China has increased by 3%-8% year by year, and it is as high as every 10 years It has become a public health issue of increasing concern; although the incidence of MM in China is lower than that in foreign countries, in recent years, due to air pollution, the atmospheric ozone layer ha...

AI Technical Summary

Problems solved by technology

[0005] Currently, the clinical diagnosis of MM mainly relies on the ABCDE criteria of the naked eye (lesions with asymmetry, irregular boundary, unclear boundary, inconsistent color, diameter greater than 0.6cm, etc.), and its reliability is only 60%-75%. There are many problems: first, there is a lack of quantitative indicators, which are greatly affected by human and subjective factors; second, early MM smaller than 0.6 cm is not considered; third, the clinical manifestations of some benign melanomas are similar to MM; fourth, although Pathological biopsy is the gold standard for the diagnosis of MM. Blindly performing surgical biopsy (which takes a long time to report the diagnosis and is completed in 2-3 days) or surgical resection, especially for toe and subnail lesions, will bring many unnecessary complications to the patient. Pain and iatrogenic trauma, and more seriously, MM patients are prone to lymphatic and hematogenous metastasis due to surgical trauma or recurrence due to surgical resection, which undoubtedly affect prognosis and increase mortality

The disadvantage is that the photo information of these retrospective MTs is interfered by many human factors such as ununiform light sources and imaging conditions, which directly affect the measurement accuracy and the comparability of data between groups. The diagnostic parameters of benign and malignant melanomas formulated There will inevitably be bias in the value

[0010] To sum up, there are no reports on the application of multiphoton imaging technology to the segmentation, feature extraction and automatic identification of skin melanocytic tumors of yellow race skin melanocytic tumors at home and abroad, and the rapid and accurate diagnosis in vivo. Instrumentation for Cutaneous Melanoma

Images