Assessment of preload dependence and fluid responsiveness

A fluid-responsive, dependent technique, applied in vascular assessment, applications, medical science, etc., can solve the problems of decreased accuracy, not as accurate as the three-parameter model, etc.

Active Publication Date: 2010-06-30
EDWARDS LIFESCIENCES CORP
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Problems solved by technology

However, this ease of use comes at the cost of a possible drop in accuracy, since PCMs can

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  • Assessment of preload dependence and fluid responsiveness
  • Assessment of preload dependence and fluid responsiveness
  • Assessment of preload dependence and fluid responsiveness

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Embodiment Construction

[0037] Disclosed herein is a method of determining a cardiovascular parameter reflecting fluid or volume responsiveness by using a waveform data set corresponding to a signal, for example, a signal from, or proportional to, an arterial blood pressure signal or a source Any signal from an arterial blood pressure signal such as a pulse oximetry signal, Doppler ultrasound or a bioimpedance measurement device. These methods involve detecting premature ventricular or atrial contractions and removing these contractions from the waveform data set prior to calculating cardiovascular parameters. Ventricular or atrial premature contractions are detected by a variety of methods.

[0038] Also disclosed herein are methods of detecting cardiac arrhythmias using a waveform data set corresponding to a signal, e.g., a signal from, or any signal proportional to, or derived from, an arterial blood pressure signal , such as pulse oximetry, Doppler ultrasound or bioimpedance measurement devices....

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Abstract

Methods for determining a cardiovascular parameter reflecting fluid or volume changes and for detecting arrhythmia are disclosed. These methods involve receiving a waveform dataset corresponding to an arterial blood pressure, pulseox, Doppler ultrasound or bioimpedance signal and analyzing the waveform to detect premature ventrical or atrial contractions. Premature ventrical or atrial contractions are detected, for example, by comparing parameters of individual cardiac cycles to the parameters of other or average cardiac cycles. If any premature ventrical or atrial contractions are present, they are removed from the waveform dataset. Once any the premature ventrical or atrial contractions are removed, a cardiovascular parameter reflecting fluid or volume changes using the modified waveform dataset is calculated. In the method for determining arrhythmia, if the number of premature ventrical or atrial contractions exceeds a predetermined arrhythmia threshold, a user such as a medical professional is notified.

Description

[0001] Priority claims under 35 U.S.C. §119 [0002] This patent application claims priority to Provisional Application No. 60 / 955,588, filed August 13, 2007, assigned to the present assignee and expressly incorporated herein by reference. Background technique [0003] Indicators—such as stroke volume (SV), cardiac output (CO), end-diastolic volume, ejection fraction, stroke volume variability (SVV), pulse pressure variability (PPV), and systolic pressure variability (SPV), etc. etc. - important not only for the diagnosis of disease, but also for "real-time" monitoring of preload-dependent, fluid-responsive, or volume-responsive states in human and animal subjects. Consequently, there are few hospitals that do not use some form of equipment to monitor one or more of these cardiac parameters. Many techniques - including invasive techniques, non-invasive techniques, and combinations thereof - are in use, and even more have been suggested in the literature. [0004] Many techni...

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Application Information

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IPC IPC(8): A61B5/021
CPCA61B5/021A61B5/726A61B5/02108
Inventor F·哈帝布L·戴德里安L·罗特里克
Owner EDWARDS LIFESCIENCES CORP
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