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New application of p-hydroxyl cinnamic acid

A para-hydroxycinnamic acid and virus technology, applied in the fields of bursal disease, chronic respiratory disease, and avian influenza caused by livestock and poultry viruses or bacteria, can solve the lack of vaccines, and no hydroxycinnamic acid drugs against livestock and poultry viruses or Anti-bacterial disease reports and other issues, to ensure food safety, solve food antibiotic residues, and improve competitiveness.

Active Publication Date: 2011-10-05
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In 2005, the Ministry of Agriculture issued a document prohibiting the application of broad-spectrum drugs (viralin, amantadine, rimantadine, acyclovir) used by humans to livestock and poultry drugs to prevent the transfer of antiviral drug resistance from livestock to humans However, some infectious diseases in my country still lack effective vaccines to control (such as respiratory reproductive syndrome, porcine myocarditis, pig unknown high fever, etc.), so it is urgent to develop effective drugs to prevent these diseases
[0006] There is no report about the use of p-hydroxycinnamic acid drugs for anti-viral or anti-bacterial diseases in livestock and poultry

Method used

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  • New application of p-hydroxyl cinnamic acid
  • New application of p-hydroxyl cinnamic acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Content of p-hydroxycinnamic acid in the present invention: p-hydroxycinnamic acid 25mg / ml. Its preparation process is as follows:

[0025] Weigh according to the above parts by weight, fully dissolve with 30% absolute ethanol, add 20% Tween-20 and 50% water, mix evenly, divide into bottles, and obtain an oral liquid preparation.

Embodiment 2

[0027] The content of p-hydroxycinnamic acid in the present invention: p-hydroxycinnamic acid 20mg / ml. Its preparation process is as follows:

[0028] Weigh according to the above parts by weight, fully dissolve with 30% absolute ethanol, add 20% Tween-20 and 50% water, mix evenly, divide into bottles, and obtain an oral liquid preparation.

Embodiment 3

[0030] The p-hydroxycinnamic acid content of the present invention: p-hydroxycinnamic acid 35mg / ml. Its preparation process is as follows:

[0031] Weigh according to the above parts by weight, fully dissolve with 30% absolute ethanol, add 20% Tween-20 and 50% water, mix evenly, divide into bottles, and obtain an oral liquid preparation.

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PUM

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Abstract

The invention discloses a new application of p-hydroxyl cinnamic acid in preparing a medicament for preventing and curing viral diseases or bacterial diseases of livestock and poultries. The product can prevent and cure viral and bacterial diseases of the livestock and the poultries and improve the production performance of the livestock and the poultries. Proved by in vivo and in vitro experiments, the p-hydroxyl cinnamic acid has the effects of preventing and curing diseases caused by mycoplasma gallisepticums, cow escherichia coli, and the like. Proved by in vivo experiments, the p-hydroxyl cinnamic acid has the effects of preventing and curing Fabricius bursal viral diseases of the livestock and the poultries, avian mycoplasmosis and avian influenza H9 and H5 subtype virus infections.

Description

technical field [0001] The present invention relates to a new use of p-hydroxycinnamic acid, in particular to the application of p-hydroxycinnamic acid in the preparation of medicines for preventing and treating viral and bacterial diseases of livestock and poultry, especially for bursal disease, avian influenza, and Chronic Respiratory Disease. Background technique [0002] In recent years, as the safety of livestock products has attracted more and more attention from consumers, the production of pollution-free livestock products has become an inevitable trend in the development of animal husbandry. The registration and management of veterinary drugs in developed countries are becoming increasingly strict. The European Union announced in 2006 that antibiotics would no longer be used as production-promoting additives, and many veterinary drugs were banned. Several types of green additives such as enzyme preparations, probiotics, and Chinese herbal medicines have subsequentl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/192A61P31/12A61P31/04A61P31/16A61P11/00A61P31/14
Inventor 何润春何诚张发明李树梅欧长波
Owner CHINA AGRI UNIV
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