Active ingredient of psoralen and preparation method thereof

Abstract

The invention discloses an active ingredient of a natural medicament and a preparation method thereof. The active ingredient is characterized in that: the psoralen content is 90 to 97 percent; the active ingredient contains two impurities; and the impurity corylifolinin content is 3 to 8 percent, and the impurity bakuchiol content is less than 1 percent. Preferably, the psoralen content is 95 to 97 percent; the impurity corylifolinin content is 3 to 4.5 percent, and the impurity bakuchiol content is less than 0.5 percent. More preferably, the psoralen content is 96 to 97 percent; the impurity corylifolinin content is 3 to 4 percent, and the impurity bakuchiol content is less than 0.1 percent. Pharmacological experiments prove that the active ingredient has excellent effect of treating male erectile dysfunction.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an active ingredient of psoralen traditional Chinese medicine. Background technique [0002] The "Measures for the Administration of Drug Registration" implemented on October 1, 2007 gave greater encouragement to the research and development of innovative drugs, and the number of domestic innovative drug applications also showed a clear upward trend. However, compared with the research on new drug impurities in developed countries, there is still a certain gap in the research level of our country. The main gap in impurity research is reflected in the systematicness and standardization of impurity research. This directly limits the level of drug research and the improvement of drug quality in our country. It is an urgent problem for many medical workers to clarify the research purpose, research ideas and related technologies for impurities. [0003] The traditional Chinese med...

AI Technical Summary

Problems solved by technology

But so far there is no new drug prepared from the active ingredients extracted from psoraleae, especially the research on the impurities of the active ingredients

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