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Powder conditioning of unit dose drug packages

A unit dose and drug technology, applied in the direction of drug equipment, packaging, transportation and packaging, etc., can solve the problem of different doses of patients

Inactive Publication Date: 2010-09-15
NOVARTIS AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This can result in different doses given to the patient due to the different results of the ejected dose from the end of the preparation release test to the time of dosing

Method used

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  • Powder conditioning of unit dose drug packages
  • Powder conditioning of unit dose drug packages
  • Powder conditioning of unit dose drug packages

Examples

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Embodiment Construction

[0016] It must be noted that, as used in this specification, singular forms include plural referents unless the context clearly dictates otherwise.

[0017] In describing and claiming the present invention, the following terms are used according to the definitions set out below.

[0018] definition

[0019] Unless otherwise stated, the terms used herein are defined as follows. Unless explicitly defined herein, standard terms are given their ordinary and conventional meanings as understood by those of ordinary skill in the art.

[0020] The term "conditioning" is used to describe the process of causing a powder to disperse more uniformly, exhibiting less agglomeration than an unconditioned powder. "Deagglomeration" is used interchangeably to refer to conditioning.

[0021] A composition "suitable for pulmonary delivery" refers to a composition that is capable of being aerosolized and inhaled by an individual such that some of the aerosolized particles reach the lungs (eg, ca...

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Abstract

The invention provides techniques for treating or conditioning powders subsequent to their packaging to facilitate extraction of the powders from their packaging.

Description

[0001] Cross References to Related Applications [0002] This application claims priority under 35 U.S.C. §119(e) based on Provisional Application No. 61 / 000,627, filed October 25, 2007, which is incorporated herein by reference in its entirety. field of invention [0003] The present invention provides, inter alia, methods for conditioning powder compositions in blisters or other devices to improve powder dispersibility. The present invention also provides various apparatuses for accomplishing this purpose. Background of the invention [0004] Patient needs for effective therapy have led to the development of various techniques for delivering pharmaceutical agents to patients. One traditional technique involves the oral delivery of pharmaceutical formulations in the form of pills, capsules, and the like. Inhalable delivery, in which a patient inhales an aerosolized pharmaceutical formulation either orally or nasally to deliver the formulation to the patient's respiratory ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M15/00B65B1/30
CPCA61M15/0028A61M2015/0005A61M2015/001A61M2202/064A61M2015/0006A61M15/0005A61M15/0006A61M15/001
Inventor S·塞莎德里B·方S·帕拉科达蒂C·C·阿纳克莱托二世P·瑞奇A·J·伯克尔D·J·帕克斯G·斯托特
Owner NOVARTIS AG
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