Chinese medicinal composition and preparation for loosening bowel and relieving constipation and preparation method thereof

A technology of laxative and traditional Chinese medicine preparations, applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as aggravating constipation, physical weakness of the elderly, and achieve fast onset of effect and easy swallowing. , quantitative and accurate effect

Inactive Publication Date: 2010-09-22
GENERAL HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many scholars do not advocate the use of these laxatives, because they can aggravate constipation and make the elderly weaker after stopping the medicine

Method used

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  • Chinese medicinal composition and preparation for loosening bowel and relieving constipation and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] The preparation of embodiment 1 medicine capsule of the present invention

[0054] Raw material and dosage:

[0055] Cistanche 20g, radish seed 15g, cassia seed 15g, Atractylodes macrocephala 20g.

[0056] Preparation:

[0057] (1) Weigh each crude drug according to the above-mentioned dosage, first extract Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, Semen Cassiae and Semen Radix with reflux of 10 times of ethanol twice for 1 hour and 2 hours respectively.

[0058] (2) Add the reflux extract of step (1) to anhydrous sodium sulfate for dehydration, leave it to stand overnight, filter (80 mesh sieve) to obtain volatile oil, and dregs for subsequent use;

[0059] (3) Add the dregs of step (2) into Cistanche cistanche, decoct and extract twice, the first time for 1 hour, and the second time for 2 hours, the amount of water added is 10 times the amount, and the medicinal liquid obtained from the two extractions is mixed and spray-dried to obtain dry po...

Embodiment 2

[0062] Embodiment 2 capsule preparation of the present invention

[0063] Raw material and dosage:

[0064] Cistanche 10g, radish seed 20g, cassia seed 20g, Atractylodes macrocephala 10g.

[0065] Preparation:

[0066] (1) Weigh each crude drug according to the above-mentioned dosage, first extract Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, Semen Cassiae and Semen Radix with reflux of 10 times of ethanol twice for 1 hour and 2 hours respectively.

[0067] (2) Add the reflux extract of step (1) to anhydrous sodium sulfate for dehydration, leave it to stand overnight, filter (80 mesh sieve) to obtain volatile oil, and dregs for subsequent use;

[0068] (3) Add the dregs of step (2) into Cistanche cistanche, decoct and extract twice, the first time for 1 hour, and the second time for 2 hours, the amount of water added is 10 times the amount, and the medicinal liquid obtained from the two extractions is mixed and spray-dried to obtain dry powder for use;

...

Embodiment 3

[0071] Embodiment 3 Preparation of pharmaceutical granules of the present invention

[0072] Preparation:

[0073] Weigh the crude drug according to the following dosage, soak the crude drug of the present invention in water for 20-30 minutes according to the conventional method, add 3 times the amount of water to boil and keep boiling for 10-15 minutes, take the medicinal liquid; add 3 times the amount of water Keep boiling for 10-15 minutes after decocting, take the liquid medicine; mix and filter the two liquid medicines, concentrate to a thick paste with a relative density of 1.3-1.34, spray granulate, and dry. Subpackage.

[0074] Raw material and dosage:

[0075] Cistanche 25g, radish seed 10g, cassia seed 10g, Atractylodes macrocephala 25g.

[0076] Clinical experiment of the present invention and result analysis:

[0077] Case: A patient with constipation over the age of 55 was selected; the course of the disease was over 1 year; the stool was dry and hard to defec...

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Abstract

The invention relates to a Chinese medicinal composition for loosening bowel and relieving constipation, which is prepared from the following raw materials in part by weight: 10 to 25 parts of desertliving cistanche, 10 to 20 parts of radishseed, 10 to 20 parts of cassia seed, and 10 to 25 parts of bighead atractylodes rhizome. The prescription of the Chinese medicament composition has the advantages of precise formula, obvious effect, wide source of raw material medicaments, and low cost. Due to simple formula, the medicament quality control is simple. The Chinese medicinal composition is prepared into a soft capsule preparation according to the characteristics of active ingredients thereof, the quantification is accurate, after the composition is disintegrated in vivo, the contents can be quickly absorbed in a liquid form by the body; and the soft capsule has smooth surface and good mouthfeel, and is easy to take. Through clinically primary pharmacodynamic validation, the composition has definite curative effect particularly on middle and old aged constipation patients, quick response, no toxic or side effect, safety, effectiveness and safe portability, and convenient . The clinical experiments prove that the Chinese medicinal composition has the effective rate of over 90 percent and has excellent application prospects and market prospects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, specifically a traditional Chinese medicine composition for moistening bowels and laxatives for middle-aged and elderly patients with constipation, and a Chinese medicine preparation prepared by using the composition. The invention also relates to a preparation method of the Chinese medicine preparation. It belongs to the field of traditional Chinese medicine. Background technique [0002] Constipation is one of the common frequently-occurring diseases of middle-aged and elderly people. Many people may experience constipation in varying degrees as they grow older, which brings great harm to the physical and mental health of the elderly. The incidence rate can reach 20-30%. If constipation is not corrected for a long time and harmful substances in the rectum cannot be eliminated in time, it will have adverse effects on the human body. Constipation in the elderly can induce and aggrava...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/64A61P1/10
Inventor 杨洁郭代红刘皈阳金道山李欣陆璐陆军章徐元杰
Owner GENERAL HOSPITAL OF PLA
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