Preparation process of non-PVC-soft-bag-packaged hemofiltration replacement liquid and product

Abstract

The invention provides a preparation process of non-PVC-soft-bag-packaged hemofiltration replacement liquid and a product. The preparation process is characterized by comprising the following steps: a. preparing medicine liquid: adding water for injection into a tank for high-concentration preparation, and then adding anhydrous glucose, and stirring to be dissolved; then adding 0.05% (W / V) of activated carbon, and holding at a temperature of 40 DEG C-70 DEG C, stirring and de-carbonizing for 30 minutes; removing carbon through titanium rod filtration, taking clear liquid to be put in a tank for dilution preparation, and adding the water for injection to the full amount, and evenly stirring; b. filling: filtering through a filter, bag-making and filling in a non-PVC soft plastic infusion bag with a double-pipe and double-valve structure, adding a stopper and sealing, wherein the reserving space of the soft infusion bag is 15% or above 200ml; c. sterilizing; and d. packaging. Enough liquid adding space is reserved, the double-pipe and double-valve structure can facilitate to add liquid so as to prevent the secondary pollution and facilitate the clinical flexible adjustment of prescriptions; and the non-PVC soft infusion bag does not contain plasticizers, adhesives and other substances harmful to the human body, and does not introduce new harmful substances.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a preparation process and product of hemofiltration replacement fluid packaged in a non-PVC soft bag. Background technique [0002] Hemofiltration replacement fluid is a special replacement drug for hemofiltration, hemodiafiltration and continuous blood purification treatment. The patient uses a large amount each time, generally about 2000ml to 4000ml each time. At present, there are very few types of filtration replacement drugs used in clinical blood purification technology, and most hospitals basically prepare them manually by nurses. It takes more than half an hour for a nurse to prepare a bag of replacement fluid, but a bag of replacement fluid only takes It can be used by patients for an hour, but there are still problems such as inaccurate measurement and high risk of contamination. With the increasingly strict drug management in the country, hospital preparations need t...

AI Technical Summary

Problems solved by technology

Although there are a few companies in the market that can produce hemofiltration replacement fluid products, clinically, patients have different specific conditions, and when receiving hemofiltration treatment, they have different requirements for different nutrients or ion elements. The basic formula of the filtration replacement fluid cannot meet the clinical requirements, requiring medical staff to add many other ingredients to the basic hemofiltration replacement fluid formula in the later stage

However, the traditional hemofiltration replacement fluid products do not have a double valve design, no special dosing port, and the filling space is small, which cannot meet the market demand