Saliva increasing mixture

A technology for mixtures and APIs, applied in the directions of drug combinations, plant raw materials, organic active ingredients, etc., can solve the problems of Chinese patent medicines with many flavors, inconvenient preparation and use, side effects, etc., and achieve the effects of easy acquisition, rapid curative effect, and convenient pharmacy

Active Publication Date: 2012-08-15
SHANGHAI MENTAL HEALTH CENT (SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENT)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the clinical treatment of psychiatric diseases, psychotropic drugs cause dry mouth due to their blocking of M cholinergic receptors, which is the most common adverse drug reaction, and there is a lack of effective treatment methods. Although the symptoms vary in severity, However, it has a great impact on the patient's quality of life, and affects the patient's compliance with medication, which is not conducive to the recovery of the disease.
[0004] At present, although there are also some medicines for treating dry mouth caused by taking psychotropic drugs, the effect is not very obvious, and there are many medicinal flavors in Chinese patent medicines, which are not easy to prepare and use, and some medicines can also cause other side effects.
Drugs for the treatment of dry mouth caused by taking psychotropic drugs have not been reported yet

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Preparation of a liquid-increasing mixture (1)

[0018] 150 grams of Scrophulariae, 150 grams of raw land, 180 grams of Dendrobium, 150 grams of Ophiopogon japonicus, 18 grams of trichosanthes, 18 grams of rhubarb, add water and boil twice, add 8 times the amount of water for the first time and boil, keep for 45 minutes after boiling, and drink Pass through a 120-mesh sieve, add 5 times the amount of water for the second time to boil, keep for 45 minutes after boiling, pass the concoction through a 120-mesh sieve, combine two concoctions, concentrate to 2500ml, let stand for 16 hours, take the supernatant and pass through 120-mesh Sieve and concentrate to 1000ml. Take 0.3 g of benzoic acid, dissolve it with an appropriate amount of 95% ethanol, add it to the liquid medicine, stir evenly, boil, hot fill, sterilize, and distribute for use.

Embodiment 2

[0019] Example 2 Preparation of a liquid-increasing mixture (two)

[0020] 200 grams of Scrophulariae, 200 grams of raw land, 220 grams of Dendrobium, 200 grams of Ophiopogon japonicus, 22 grams of trichosanthes, 22 grams of rhubarb, add water and boil twice, add 8 times the amount of water for the first time and boil, keep it for 45 minutes after boiling, concoction Pass through a 120-mesh sieve, add 5 times the amount of water for the second time to boil, keep for 45 minutes after boiling, pass the concoction through a 120-mesh sieve, combine two concoctions, concentrate to 2500ml, let stand for 16 hours, take the supernatant and pass through 120-mesh Sieve and concentrate to 1000ml. Take 0.7 g of benzoic acid, dissolve it with an appropriate amount of 95% ethanol, add it to the liquid medicine, stir evenly, boil, hot fill, sterilize, and distribute for use.

Embodiment 3

[0021] Example 3 Preparation of a liquid-increasing mixture (3)

[0022] 160 grams of Scrophulariaceae, 190 grams of raw land, 220 grams of dendrobium, 200 grams of Ophiopogon japonicus, 22 grams of trichosanthes, 22 grams of rhubarb, add water and boil twice, add 8 times the amount of water for the first time and boil, keep it for 45 minutes after boiling, concoction Pass through a 120-mesh sieve, add 5 times the amount of water for the second time to boil, keep for 45 minutes after boiling, pass the concoction through a 120-mesh sieve, combine two concoctions, concentrate to 2500ml, let stand for 16 hours, take the supernatant and pass through 120-mesh Sieve and concentrate to 1000ml. Take 0.6 g of benzoic acid, dissolve it with an appropriate amount of 95% ethanol, add it to the liquid medicine, stir evenly, boil, hot fill, sterilize, and distribute for use.

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PUM

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Abstract

The invention relates to a saliva increasing mixture which is used for treating dry mouth caused by taking psychotropic medicaments. The active ingredients of the saliva increasing mixture are mainly prepared from the following raw material medicaments in part by weight: 1,500 to 2,000 parts of figwort, 1,500 to 2,000 parts of rehmannia root, 1,800 to 2,200 parts of dendrobium, 1,500 to 2,000 parts of dwarf lilyturf root, 180 to 220 parts of trichosanthes root and 180 to 220 parts of rhubarb; and the raw material medicaments of the saliva increasing mixture also comprise 3 to 7 parts of benzoic acid. The invention also provides the application of saliva increasing mixture used for treating the dry mouth caused by taking the psychotropic medicaments. The saliva increasing mixture has the advantages that: the medicament needs less raw material medicaments; the raw material medicaments are easy to obtain; the medicament is convenient to prepare and is simple in operation; and the saliva increasing mixture has a quick and remarkable curative effect and less side effects, and is suitable for clinical application.

Description

technical field [0001] The invention relates to a medicine for treating dry mouth caused by taking psychotropic drugs, in particular to a Zengye mixture prepared from Chinese herbal medicines. Background technique [0002] Psychotropic drugs have experienced the application from classic to atypical psychotropic drugs, and their curative effect and reduction of drug side effects are affirmed and recognized, but sufficient attention should still be paid to their side effects. [0003] In the clinical treatment of psychiatric diseases, psychotropic drugs cause dry mouth due to their blocking of M cholinergic receptors, which is the most common adverse drug reaction, and there is a lack of effective treatment methods. Although the symptoms vary in severity, However, it has a great impact on the quality of life of the patient, and affects the patient's compliance with medication, which is not conducive to the recovery of the disease. [0004] At present, although there are also ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P43/00A61K31/192
Inventor 周龙标周康王祖承顾牛范严和骎张良栋郭莲舫王义方笪志民梁志健肖泽萍徐一峰宋立升赵敏谢斌姚培芬赵根祥毛叶萌张建明
Owner SHANGHAI MENTAL HEALTH CENT (SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENT)
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