Preparation method of hydrogel cataplasm and prepared cataplasm with effect of relieving swelling and pains

Abstract

The invention relates to a preparation method of hydrogel cataplasm and prepared cataplasm with the effect of relieving swelling and pains. The prepared cataplasm comprises glycerol, polyvinylpyrrolidone, crosslinked povidone, sodium polyacrylate, aluminum glycinate, sodium carboxymethylcellulose, ethanol, borneol, citric acid, polyvinyl alcohol, sodium benzoate and purified water. The preparation method comprises the following steps: (1) dissolving borneol in ethanol for later use; (2) dissolving citric acid in 14.5-35 parts of water for later use; (3) dissolving sodium benzoate in water, adding polyvinyl alcohol, and heating to dissolve; and adding the rest purified water; and (4) pouring glycerol into a container, sequentially adding polyvinylpyrrolidone, crosslinked povidone, sodium polyacrylate, aluminum glycinate and sodium carboxymethylcellulose, stirring uniformly, adding the borneol ethanol solution, and stirring uniformly; and obtaining a gel. The preparation method provided by the invention is convenient, and has the advantages of simple process, operation at room temperature, environmental friendliness, high safety, no environmental pollution, and no waste emission during the production process. The entire process is harmless to operators.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a swelling-reducing and analgesic cataplasm ointment. Background technique [0002] With the continuous development of the pharmaceutical industry, Babu ointment has gradually been more widely used in my country's pharmaceutical market, because of its large drug load, good transdermal effect, sustainable drug delivery, measurable drug components, and controllable quality , good air permeability, and low skin irritation, it has become an ideal transdermal drug delivery carrier. Compared with traditional plasters, the use of organic solvents in the production process is reduced, thereby avoiding damage to the health of workers and pollution to the environment. [0003] Papua ointment refers to the external preparation made by mixing the extracts of medicinal materials, drugs and suitable hydrophilic substrates, and then applying them on cloth. Commonly used base materials for cat...

AI Technical Summary

Problems solved by technology

[0004] Since the original formulation of Xiaozhong Analgesic Ointment is a pressure-sensitive rubber patch, organic solvents are used in the process, which will cause skin damage after long-term use. Organic solvents in production will pollute the environment and other disadvantages.

The hydrogel babu ointment is used to improve the swelling and analgesic ointment. The matrix excipients used have high water content and good penetration effect, and have the advantages of good biocompatibility with the skin, which can overcome the biocompatibility of the ointment prepared by traditional pressure-sensitive rubber poor disadvantage

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