Chinese herbal medicinal external application preparation and preparation method and application thereof

A technology of external preparations and Chinese herbal medicines, applied in the direction of medical formulas, medical preparations containing active ingredients, antifungal agents, etc., can solve problems such as irreversible, toxic and side effects, and achieve the effect of not easy to relapse, less toxic and side effects, and easy to apply

Inactive Publication Date: 2011-10-05
ZHEJIANG FORESTRY UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods have certain toxic and

Method used

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  • Chinese herbal medicinal external application preparation and preparation method and application thereof
  • Chinese herbal medicinal external application preparation and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0033] The prescription of the external preparation is: 20 grams of tripterygium wilfordii, 20 grams of mimosa, 10 grams of pecan exocarp, 15 grams of clover, 10 grams of Zanthoxylum bungeanum, 15 grams of Daqingye, 5 grams of neem bark, and 5 grams of centipede.

[0034] The preparation method of the preparation of the present invention is as follows: the medicinal materials are respectively pulverized into coarse powder, and passed through a 20-mesh sieve; the coarse medicinal powder is mixed according to the above-mentioned formula ratio and extracted 3 times with 70% ethanol under reflux, each time for 40 min, if the dry weight of the medicinal materials is 1 kg, the amount of solvent used is 8 L; filter with suction, combine the extracts, in a water bath at a temperature of 70°C, and wait until the flow rate of the concentrated solution is 250 mL min -1 Under the conditions of vacuum thin film concentration device for flash concentration, to obtain a concentrated liquid co...

Embodiment 2

[0036] The external preparation prescription is: tripterygium wilfordii 22 grams, mimosa 22 grams, pecan exocarp 10 grams, clover 13 grams, pepper 8 grams, Folium 13 grams, neem bark 6 grams, centipede 6 grams.

[0037] The preparation method of the preparation of the present invention is as follows: the medicinal materials are respectively pulverized into coarse powder, and passed through a 20-mesh sieve. The coarse powder of the medicinal material was mixed according to the above formula ratio, and then extracted twice with 60% ethanol under reflux, each time for 50 min. If the dry weight of the medicinal material was 1 kg, the amount of solvent used was 10 L; 80°C, the flow rate of the liquid to be concentrated is 300 mL·min -1 Under the conditions of vacuum thin film concentrating device for flash concentration, to obtain a concentrated liquid containing 2 g of raw medicinal materials per mL of concentrated liquid, and then keep the concentrated liquid below 70°C for rotar...

Embodiment 3

[0039] 18 grams of tripterygium wilfordii, 18 grams of mimosa, 12 grams of pecan exocarp, 16 grams of clover, 12 grams of pepper, 16 grams of Daqingye, 4 grams of neem bark, and 4 grams of centipede.

[0040] The preparation method of the external preparation is as follows: respectively pulverizing medicinal materials into coarse powder and passing through a 20-mesh sieve. The coarse powder of medicinal materials was mixed according to the above formula ratio, and then refluxed with 80% ethanol for 3 times, each time for 30 min. If the dry weight of medicinal materials was 1 kg, the amount of solvent used was 9 L; 70°C, the flow rate of the liquid to be concentrated is 250 mL·min -1 Under the conditions of vacuum thin film concentration device for flash concentration, to obtain a concentrated liquid containing 3 g of raw medicinal materials per mL of concentrated liquid, and then keep the concentrated liquid below 70 ° C, continue to rotate the thin film concentration, vacuum ...

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Abstract

The invention discloses a Chinese herbal medicinal external application preparation and a preparation method and application thereof, belonging to the technical field of Chinese medicinal preparations. The preparation is characterized by consisting of the following substances in parts by weight: 15-25 parts of common threewingnut root, 15-25 parts of mimosa pudica, 6-15 parts of kiskatom epicarp,10-20 parts of hemsley rockvine root, 6-15 parts of pepper, 10-20 parts of dyers woad leaf, 3-8 parts of chinaberry bark and 3-8 parts of centipede. The Chinese herbal medicinal external application preparation has the effects of relieving fever, relieving internal heat, inducing diaphoresis to dispel wind, detoxifying, eliminating toxicants, sterilizing, eliminating dampness, resisting inflammation, eliminating the swelling, relieving itching, removing ringworm, regulating immunity, improving microcirculation and the like, has remarkable healing effects on psoriasis, eczema, herpes, skin itch, dermatophytosis, athlete's foot and the like, and has the advantages of high cure rate, extensive treatment, no damage to human skin, small toxic or side effect, simple preparation method, using safety and convenience and low production cost. The preparation plays in role in treating the malignant disease with poisonous agents, and has the characteristics of capability of treating both principal and secondary aspects of a disease, remarkable healing effect, difficult recurrence after curing and easiness for application.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, in particular to a Chinese herbal medicinal preparation for external use, a preparation method and application. Background technique [0002] Diseases caused by fungal infections are called mycoses, and the most common forms of candidiasis and dermatophytosis are caused by fungi from the normal flora of the human body. The common fungal infectious skin disease is tinea pedis, which is generally contagious. If the fungal infection has exudate, it may be complicated by bacterial infection. Clinically, pathogenic fungi are divided into superficial fungi and deep fungi. Superficial fungi only invade the skin, hair, and nails, while deep fungi can invade human skin, mucous membranes, deep tissues and internal organs, and even cause disseminated infections throughout the body. [0003] Athlete's foot is divided into two types: superficial infection and deep infectio...

Claims

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Application Information

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IPC IPC(8): A61K36/855A61K36/758A61P17/00A61P17/04A61P17/06A61P31/10A61K35/64A61K35/648
Inventor 袁珂吴叶平林晓春
Owner ZHEJIANG FORESTRY UNIVERSITY
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