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Application of valeriana jatamansi jones or extracts thereof in preparation of medicine for lowering fat and protecting liver
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A technology of spider incense and extract, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of undiscovered spider incense lowering blood lipid and liver protection, drug effect difference, etc.
Inactive Publication Date: 2014-04-02
SOUTHWEST JIAOTONG UNIV
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In addition, although valerian and spider incense belong to different plants of the same genus, they have different medicinal effects. At present, there are no relevant reports on the blood lipid-lowering and liver-protecting effects of spider incense at home and abroad.
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Embodiment 1
[0017] Example 1 The preparation of the spider incense extract of the present invention
[0018] Weigh 200g of the original medicinal material fine powder of spider incense, use 80% ethanol, 10 times the amount of ethanol, 40KHz, extract 90min ultrasonic extraction twice, filter, combine the two filtrates, 40 ° C rotary steam concentration to liquid extract, and 0.5% CMC -Na solution is fixed to 660mL, which is equivalent to containing 0.3g of crude drug per milliliter.
Embodiment 2
[0019] Example 2 The preparation of the spider incense extract of the present invention
[0020] Weigh 200g of the original medicinal material fine powder of spider incense, use 95% ethanol, 5 times the amount of ethanol, 59KHz, extract 30min ultrasonic extraction twice, filter, combine the two filtrates, 40 ° C rotary evaporation concentrated to liquid extract, and 0.5% CMC -Na solution is fixed to 660mL, which is equivalent to containing 0.3g of crude drug per milliliter.
Embodiment 3
[0021] Example 3 The preparation of the spider incense extract of the present invention
[0022] Weigh 200g of the original medicinal material fine powder of spider incense, use 60% ethanol, 15 times the amount of ethanol, 80KHz, extract 60min, ultrasonically extract twice, filter, combine the two filtrates, 40°C rotary steaming and concentrating to liquid extract, and 0.5% CMC -Na solution is fixed to 660mL, which is equivalent to containing 0.3g of crude drug per milliliter.
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Abstract
The invention provides application of valeriana jatamansi jones or extracts thereof in the preparation of a medicine for lowering the fat and protecting the liver. The invention also provides a pharmaceutical composition for lowering the fat and protecting the liver. Animal experiments prove that the valeriana jatamansi jones or the extracts thereof has / have the functions of reducing blood fat and serum AST (aspartate transaminase), ALT (alanine transaminase), and can be used for the treatment of hyperlipidemia with definite efficacy thereby providing a new choice the clinic.
Description
technical field [0001] The invention relates to a new application of spider incense or its extract, in particular to a new application in the preparation of liver-protecting and lipid-lowering drugs, which belongs to the field of medicines. Background technique [0002] Spider incense (Valeriana jatamansi Jones) is a plant of Valerianaceae (Valerianaceae) genus Valeriana (Valeriana Linn). "Collection", Stinky Medicine "Common Herbal Medicine Treatment Handbook", Vanilla Seed "Shaanxi Chinese Herbal Medicine", etc. Spider incense was once recorded in "Southern Yunnan Materia Medica" and "Compendium of Materia Medica", as well as in the 1977 and 2010 editions of "Chinese Pharmacopoeia (Part One)", saying that it is "warm in nature, pungent in taste, slightly bitter, and warm in heart, spleen, and stomach." Meridian, functions of regulating qi and relieving pain, eliminating food and relieving diarrhea, expelling wind and dampness, calming the nerves, and is used for abdominal...
Claims
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Application Information
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