Acidic buffering sterilization gel for vagina gynaecologically

A sterilizing gel and vaginal technology, which is applied in the field of gynecological vaginal gel preparations, can solve problems such as vaginal microecological flora imbalance, improper cleaning methods, and vigorous fungal growth, so as to promote the secretion of estrogen and ensure the uniformity of quality , maintain natural moisturizing effect

Active Publication Date: 2012-09-05
石家庄诺利达医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Under normal circumstances, the female vagina is acidic, which can inhibit the reproduction of pathogenic bacteria and has the ability of self-purification and antibacterial, but due to various reasons, 40% of them are due to improper cleaning methods, because many cleaning lotions are alkaline liquids, long-term use It will destroy the normal acidic environment of the vagina and cause the vaginal micro-ecological flora to be in an imbalanced state, causing vaginitis to become the most common disease in gynecology; the abuse or use of antibiotics will make bacteria resistant, and kill a large number of beneficial bacteria, destroying vaginal bacteria The balance of the swarm, resulting in the vigorous growth of fungi, and gynecological diseases are stubborn and difficult to cure
[0003] The suppositories or lotions currently used in the market may cause vaginal dryness and discomfort after use due to defects in formula and dosage form; the area of ​​action of the drug is limited to a certain position, and the vaginal folds cannot play a good role; suppositories still cannot be used after use Sufficiently absorbed leaving residue, etc.
[0004] Chinese patent application CN101773516A discloses a vaginal acidic buffer gel preparation and its preparation method and application. In the case of rampant bacteria, it cannot play a fundamental role

Method used

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  • Acidic buffering sterilization gel for vagina gynaecologically
  • Acidic buffering sterilization gel for vagina gynaecologically
  • Acidic buffering sterilization gel for vagina gynaecologically

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Take 2g of V80, 120g of glycerin, 10g of carbomer (940), 15g of polycarbophil, 2g of triethanolamine, 0.1g of vitamin E, 0.1g of peppermint, and 830g of water. First mix glycerin and water evenly, add V80 and stir evenly, then add carbomer (940) and polycarbophil and let stand for 6-8 hours, stir to fully dissolve, then add triethanolamine, stir to dissolve, and finally add vitamins E and mint can be dissolved by stirring thoroughly, and then divided into 3~5g syringes.

Embodiment 2

[0015] Take 2.5 g of single and double chain compound quaternary ammonium salt, 124 g of glycerin, 14 g of carbomer (940), 18 g of polycarbophil, 2.4 g of triethanolamine, 0.25 g of vitamin E, 0.25 g of peppermint, and 835 g of water. First mix glycerin and water evenly, add single and double chain compound quaternary ammonium salt and stir evenly, then add carbomer (940) and polycarbophil and let stand for 6-8 hours, stir to dissolve fully, then add triethanolamine, stir to dissolve , And finally add vitamin E and mint, fully stir to dissolve it, and pack it into a bolus of 3 to 5g.

Embodiment 3

[0017] Take 5 g of single and double chain compound quaternary ammonium salt, 125 g of glycerin, 15 g of carbomer (940), 20 g of polycarbophil, 3 g of triethanolamine, 0.3 g of vitamin E, 0.3 g of peppermint, and 840 g of water. First mix glycerin and water evenly, add single and double chain compound quaternary ammonium salt and stir evenly, then add carbomer (940) and polycarbophil and let stand for 6-8 hours, stir to fully dissolve, then add triethanolamine, stir Dissolve, add vitamin E and mint at last, stir well to dissolve, and pack into 3~5g bolus injectors.

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Abstract

The invention discloses an acidic buffering sterilization gel for vagina gynaecologically. The gel consists of the following substances in parts by weight: 0.2-0.5 part of bactericide, 12-12.5 parts of glycerol, 83-84 parts of water, 1-1.5 parts of Carbomer, 1.5-2 parts of polycarbophil, 0.2-0.3 part of triethanolamine, 0.01-0.03 part of vitamin E, and 0.01-0.03 part of mint. The acidic bufferingsterilization gel has the advantages that: pathogenic bacteria can be quickly and effectively killed, inflammatory symptoms can be quickly and effectively relieved, normal pH value of the vagina is maintained, elasticity of the inner wall in the vagina can be kept, wetness of the vagina is maintained, and drug tolerance and drug resistance do not generate.

Description

Technical field [0001] The invention relates to a gynecological vaginal gel preparation, in particular to an acid buffer sterilization gel for gynecological vagina, belonging to the field of medicine. Background technique [0002] Under normal circumstances, women’s vaginas are acidic, which can inhibit the growth of pathogenic bacteria and have the ability to self-purify and anti-bacterial. However, due to various reasons, 40% of them are due to improper cleaning methods, because many cleaning lotions are alkaline liquids and long-term use It will destroy the normal acidic environment of the vagina and cause the vaginal microecological flora to be in a state of imbalance, causing vaginitis to become the most common disease in gynecology; abuse or use of antibiotics will make the bacteria resistant to bacteria, and kill a large number of beneficial bacteria, destroying vaginal bacteria The balance of the group causes the fungus to grow vigorously, and the gynecological diseases a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/00A61K47/32A61K47/46A61P15/02
Inventor 李桂霞张建康任双军任晓华
Owner 石家庄诺利达医疗器械有限公司
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