Medical moist composite dressing and preparation method thereof

A manufacturing method, wet technology, applied in medical science, non-woven fabrics, textiles and papermaking, etc., can solve the problems that cannot meet the needs of wound healing, and achieve the effect of less replacement times, less damage, and good mechanical properties

Inactive Publication Date: 2012-02-15
CHINESE TEXTILE ACAD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At this time, moist dressings such as sodium alginate cannot meet the needs of wound healing.

Method used

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  • Medical moist composite dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] First, the polylactide slices are dried under vacuum (vacuum degree 750-760 mmHg) for 12 hours at a drying temperature of 120° C., and the moisture content of the slices is <80 ppm after drying. The dried polylactide slices are extruded by screw on the spinning and drawing machine, drawn in two stages, and wound to obtain polylactide filaments. The screw temperatures are: 220°C in zone 1 and 2 zones in zone 2. 230°C, 230°C in zone 3, 240°C in zone 4; the rotation speed of the spinning melt pump (0.3cc) is 16r / min; the temperature and speed of the first drafting roller are 50°C and 120m / min respectively; The temperature and speed of the rolls were 70°C and 380m / min respectively; the temperature and speed of the third drafting roll were 120°C and 600m / min respectively; the winding speed was 580m / min. The obtained fiber has a breaking strength of 5.8cN / dtex, a breaking elongation of 22.0%, and a strength retention rate of 30-50% within 2 weeks. The obtained polylactide fi...

Embodiment 2

[0032] According to the same method as described in Example 1, the polylactide staple fiber of monofilament 5dtex and 76mm is obtained, and the polylactide staple fiber and sodium alginate staple fiber (single filament fineness 1.5dtex, fiber length 10mm, fracture Strength 1.5~3.5cN / dtex) is pre-mixed according to the weight ratio of 30:70, and then through opening, mixing, carding, laying, pre-needling, lower main needle, upper main needle, heat treatment (110°C), molding, processing into needle-punched non-woven fabrics. Among them, the density of the medical composite dressing is controlled to 140g / m by adjusting the thickness of the net 2 , The water absorption rate reaches more than 10 times, and the bidirectional elongation at break> 30%. Adjust the pH of the medical composite dressing to 6.0-8.0, and then carry out gamma ray disinfection.

Embodiment 3

[0034] According to the same method as described in Example 1, obtain monofilament 2.5dtex, polylactide staple fiber of 38mm, polylactide staple fiber and sodium alginate staple fiber (single filament fineness 2dtex, fiber length 8mm, fracture Strength 1.5~3.5cN / dtex) pre-mixed according to the weight ratio of 40:60, and then through opening, mixing, carding, laying, pre-needling, lower main needle, upper main needle, heat treatment (140°C), molding, processing into needle-punched non-woven fabrics. Among them, the density of the medical composite dressing is controlled to 160g / m by adjusting the thickness of the laying net 2 , The water absorption rate reaches more than 10 times, and the bidirectional elongation at break> 30%. Adjust the pH of the medical composite dressing to 6.0-8.0, and then carry out gamma ray disinfection.

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Abstract

The invention discloses a medical moist composite dressing which comprises 20-50% of poly(glycolide-co-lactide) (PGLA) and 50-80% of sodium alginate by mass percent. According to the technical scheme disclosed by the invention, as the medical moist composite dressing comprises the PGLA and the sodium alginate, high water absorption of the sodium alginate ensures moist environments of wounds, the PGLA has good mechanical properties, a network structure is formed in the dressing, and a gel film formed by sodium alginate fibers can be put on the wounds for a long time and is not easy to damage, thus reducing the change times of the dressing and being beneficial to wound healing.

Description

technical field [0001] The invention relates to the field of medical consumables and its manufacture, in particular to a medical moist composite dressing and its manufacturing method. Background technique [0002] Textile wound dressings are one of the most important medical consumables in modern medicine. Traditional dressings mainly include gauze, sponges, bandages and other dry dressings that can expose wounds to oxygen. In 1962, Dr. Wendt of the University of London proved that wounds using wet dressings healed more naturally than those exposed to air, and the wound healing speed was significantly accelerated. A large number of basic and clinical studies subsequently supported this view. In the 1990s, high-grade wet dressings made of biological materials, polymer materials, and composite materials developed rapidly. In August 2000, the U.S. Food and Drug Administration (FDA) specially emphasized in the newly promulgated industry guidelines for wound medical supplies (ex...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/26D04H1/42D04H1/46
Inventor 李杰徐纪刚周杰曲希明崔华帅吴鹏飞史贤宁黄庆沈锂鸣
Owner CHINESE TEXTILE ACAD
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