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Single-face controlled multi-electrode cluster digital micro-fluid chip

A digital microfluidics and multi-electrode technology, which is applied to laboratory appliances, laboratory containers, chemical instruments and methods, etc., can solve the problems of increasing complexity in a quadratic relationship, large number of electrodes, difficulty in droplet movement, etc. question

Inactive Publication Date: 2012-05-02
FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For this kind of control chip, the upper and lower plates are strip electrodes, and periodic voltages need to be applied, which greatly increases the complexity of the surrounding control circuits and systems.
However, the existing two-dimensional digital microfluidic technology controlled by a unipolar plate mainly has two types: the first one is a two-dimensional unipolar plate composed of square electrode units, although the peripheral control circuit of the double layer can be simplified, but Due to the large number of electrodes, as the control accuracy increases, its complexity increases in a quadratic relationship, which is not conducive to the preparation of large-area microfluidic chips
The second is simply stacking strip electrodes vertically, and using a single electrode as a control unit to drive the droplet movement. This structure is difficult for the droplet movement due to the mutual interference of the stacked electrodes and the large distance between the electrodes.

Method used

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  • Single-face controlled multi-electrode cluster digital micro-fluid chip
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  • Single-face controlled multi-electrode cluster digital micro-fluid chip

Examples

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Embodiment Construction

[0011] Such as figure 1 Shown is a schematic diagram of the control electrode of the present invention, and the control electrode of the digital microfluidic chip of the present invention is composed of strip electrodes interlaced horizontally and vertically. The present invention takes 19 horizontal electrodes and 20 vertical electrodes as an example, but the number of electrodes described in the present invention is not limited by the number of electrodes described in this embodiment. Wherein, electrodes 1--electrodes 19 are placed in the lower layer and placed parallel to each other, and electrodes 20--electrodes 40 are placed in the upper layer. Using a cluster of electrodes as the basic control unit, a voltage is applied to control the droplet movement. For example, the droplet is formed by figure 1 Moving upwards in the lower left direction of , the droplet is initially located on electrodes 2--electrodes 5, and at the same time on electrodes 21--electrodes 24. At thi...

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Abstract

The invention belongs to a microelectronic bio-chip technology field, and concretely provides a single-face controlled multi-electrode cluster digital micro-fluid chip. The chip comprises a lower-layer core component and a upper-layer grounding component, wherein the lower-layer core component comprises a two dimensional stripe electrode cluster array which is interlaced in transversal and longitudinal grid manner and arranged in the same substrate, and an electrode insulating layer is arranged between the transversal electrode cluster array and a longitudinal electrode cluster array. The dimension of the stripe electrodes in transversal and longitudinal distribution on the substrate is controlled to be far less than that of the liquid drop, and the liquid drop is charged to control the liquid drop to move along the direction vertical to the electrode cluster while the plurality of electrodes form the electrode cluster. The chip of the invention makes the liquid drop move on the chip smoother.

Description

technical field [0001] The invention belongs to the technical field of microelectronic biochips, and in particular relates to a digital microfluidic chip. Background technique [0002] The traditional two-dimensional digital microfluidic technology needs to place the droplet between the upper and lower control plates, and apply voltage to make the droplet move between the two plates. For this kind of control chip, the upper and lower plates are strip-shaped electrodes, and periodic voltages need to be applied to them, which greatly increases the complexity of the surrounding control circuits and systems. The existing two-dimensional digital microfluidic technology controlled by unipolar plates mainly has two types: the first one is a two-dimensional unipolar plate composed of square electrode units, although the double-layer peripheral control circuit can be simplified, but Due to the large number of electrodes, as the control precision increases, its complexity increases i...

Claims

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Application Information

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IPC IPC(8): B01L3/00
Inventor 曾祥宇周嘉
Owner FUDAN UNIV
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