MRESI (multichannel rotating electrospray ionization) mass spectrometric analysis ion source

Abstract

The invention discloses an MRESI (multichannel rotating electrospray ionization) mass spectrometric analysis ion source. The ion source comprises a pedestal, a stepping motor, a coupling part, a voltage conducting part, a rear support part, a rear-end bearing, a middle shaft, a front support part, a front-end bearing, a spraying needle fixed part, spraying needles and a sample platform, wherein the pedestal supports a whole set of device, and a rotor of the stepping motor and the middle shaft are coaxial; the voltage conducting part is provided with at least one conductive contact, and the spraying needles are communicated with external voltage in an electric conductance manner through wires; the front support part is sleeved on the middle shaft and the spraying needle fixed part through the front-end bearing, the rear support part is sleeved on the middle shaft through the rear-end bearing so as to support on a coaxial direction along a revolving part of the stepping motor; the left end of the middle shaft is connected with the stepping motor through the coupling part so as to transfer the rotation to connect with the spaying needle fixed part of the right end of the middle shaft; and the spraying needle fixed part is provided with multiple grooves used for installing the spraying needles, and each spraying needle is mutually communicated with an outer placing injector through an individual pipeline. The device provided by the invention has the advantages of being capable of improving ionization efficiency, enhancing stability of mass spectrometric detection signals, being used for researching gas phase among different sprayings or liquid phase reactions as well as the detection of polycomponent of complicated samples or full component.

Description

technical field [0001] The invention relates to the field of chemical analysis, in particular to a multi-channel rotary electrospray ionization mass spectrometry ion source. Background technique [0002] Mass spectrometry is currently one of the most sensitive analytical methods and is widely used in many fields such as chemistry, environment, food, and life sciences. A mass spectrometer is usually composed of a sample introduction system, an ion source, a mass analyzer, a detector, and a data processing system, among which the role of the ion source is to ionize the sample. Because sample ionization is the premise of mass spectrometry, the development of ion source technology is directly related to the application range of mass spectrometry. There are many designs of ion sources, such as electron bombardment ion source (EI), chemical ionization source (CI), field ionization / field desorption ionization source (FI / FD), fast atom bombardment source (FAB), electrospray ion sou...

AI Technical Summary

Problems solved by technology

However, in EESI mass spectrometry, it is necessary to optimize multiple position and angle parameters between the two pipelines and the mass spectrometer inlet to obtain better sample ion signals, and the sample utilization rate is low

In addition, when EESI needs to change the spray solvent for different analytes, the operation is more cumbersome, and it is not possible to analyze samples with multiple spray solvents at the same time, so it is impossible to realize the simultaneous analysis of more components of complex samples

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