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Preparation method of nux vomica powder preparation

Nuxychnium powder and Nuxychnium technology, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., to improve drug efficacy and reduce risks

Inactive Publication Date: 2013-09-18
EAST CHINA UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this way of using medicine does not carry out any preparation treatment on the raw material Nuxychnium powder, therefore, the release of strychnine and strychnine in the drug prepared by this method is consistent with the release law in pure Nuxe seed powder

Method used

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  • Preparation method of nux vomica powder preparation
  • Preparation method of nux vomica powder preparation
  • Preparation method of nux vomica powder preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Preparation of pure Nuxychnium powder: Weigh 45g of Nuxychnium, pulverize it with a mixer for 1-2 minutes, pass through a 20-mesh sieve, and repeatedly crush the parts that have not passed through the 20-mesh sieve until all of them pass through the 20-mesh sieve to obtain a 20-mesh coarse powder Pure Nuxychon Seed Powder (with image 3 It is the scanning electron micrograph of the nuxy seed powder preparation that embodiment 1 makes).

Embodiment 2

[0038] A preparation method of Nuxychnium powder preparation, mixing three kinds of raw materials of Nuxychnium: Olibanum: Myrrh according to the mass fraction ratio of 1:1:1 and pulverizing: respectively weighing 20g of Nuxychnium, 20g of Frankincense, and 20g Myrrh, mix them and place them in a Chinese herbal medicine grinder, pulverize for 1 to 2 minutes, then spread the pulverized medicinal powder to dry, pass through a 20-mesh sieve, and repeatedly pulverize the part that has not passed through a 20-mesh sieve until all of them pass through the 20-mesh sieve. 20 mesh sieves, obtain the target product Nuxychnium powder preparation (attached Figure 4 It is the scanning electron micrograph of the nuxy seed powder preparation that embodiment 2 makes).

Embodiment 3

[0040] A preparation method of Nuxychnium powder preparation, mixing the three raw materials of Nuxychnium: Olibanum: Myrrh according to the mass fraction ratio of 1:0.5:0.5 and then pulverizing: respectively weighing 40g of Nuxychnium, 20g of Frankincense, and 20g Myrrha, (following steps are the same as embodiment 2), obtain target product Nuxychnium powder preparation (attached Figure 5 It is the scanning electron micrograph of the nuxy seed powder preparation that embodiment 3 makes).

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Abstract

The invention relates to technical field of medicament preparation, in particularly to a preparation method of a nux vomica powder preparation. The method is characterized by comprising the following steps of: mixing processed nux vomica with frankincense and myrrh in the mass fraction ratio of 1:(0.25-1.5):(0.25-1.5), and smashing together; or mixing processed nux vomica with mixed coarse powder of frankincense and myrrh according to a certain proportion, and smashing together; or mixing coarse nux vomica powder with mixed coarse powder of frankincense and myrrh according to a certain proportion, and further smashing; and smashing with a stirring machine for 1-2 minutes, spreading the smashed medicinal powder, airing, sieving with a 20-mesh sieve, and repeatedly smashing parts which do not pass through the 20-mes sieve till all powder pass through the 20-mesh sieve to obtain the nux vomica powder preparation serving as a target product. The preparation method has the positive effects that: the prepared nux vomica powder preparation has a certain control release effect, is suitable for warming channels, dredging collaterals, eliminating stagnant blood and relieving pain, and can be used for treating pain symptoms such as cold-dampness syndrome, blood stasis and qi stagnation, lowering the administration risk of the nux vomica powder, and improving a medicinal curative effect.

Description

technical field [0001] The invention relates to the technical field of medicament preparation, in particular to a new preparation method of Nuxychnium seed powder preparation. Background technique [0002] Nuxynum is a kind of traditional Chinese medicine, which has the effects of dredging collaterals, relieving pain, dispelling stagnation and reducing swelling. It is a commonly used traditional Chinese medicine for clinical treatment of rheumatism, rheumatoid arthritis and various nervous system diseases. Nuxychnium is used as medicine in two ways, one is that Nuxychnium is directly used as medicine, and the other is that Nuxychnium is powdered and used as medicine. A variety of popular Chinese patent medicines on the market, such as: Yaotongning Capsules, Fengshi Nuxomy Tablets, Shufengdingtong Pills, Jiufen, and Shujin Pills, all contain Nuxychonzi powder. The active ingredients in Strychnium are strychnine and strychnine, but strychnine and strychnine are also toxic ing...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/56A61K47/46A61P29/00
Inventor 倪力军盖群张立国陈露王媛媛方聪颖王银亮张强祖郭燕子
Owner EAST CHINA UNIV OF SCI & TECH