Application and preparation method of sibutramine in preparation of information therapeutic drug and novel drug prepared by preparation method

A chemotherapeutic drug, sibutramine technology, applied in the field of medicine, can solve rapid, arrhythmia, high blood pressure, insomnia, headache, easy to wake up, irritability, dry mouth, fear of food, constipation and interstitial Nephritis, can not be used twice, limit the treatment effect and other problems, so as to reduce the treatment cost, increase the use value and overcome the side effects

Inactive Publication Date: 2012-07-25
北京中卫神农慢性病医学研究院有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In the prior art, sibutramine is used as a chemotherapeutic drug, and there are defects that cannot be overcome so far. The first is the toxic and side effects on the human body, and its annoying adverse reactions include increased heart rate, arrhythmia, increased blood pressure, and insomnia. , headache, easy to wake up, irritability, dry mouth, fear of eating, constipation and interstitial nephritis, peripheral edema, arthritis, etc.; second, the treatment window is

Method used

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  • Application and preparation method of sibutramine in preparation of information therapeutic drug and novel drug prepared by preparation method
  • Application and preparation method of sibutramine in preparation of information therapeutic drug and novel drug prepared by preparation method
  • Application and preparation method of sibutramine in preparation of information therapeutic drug and novel drug prepared by preparation method

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Embodiment

[0044] Take sibutramine raw material (1) according to the following weight: 750 grams of sibutramine raw material (1) (content ≥ 99%), put raw material (1) into the filling machine, use microporous air-permeable paper bags according to the net weight of each bag 25 Pack into 30 bags by gram, heat-melt and seal, and make sibutramine medicine information stuffing bag (3). Simultaneously, make magnetic suspension (card) (8) container (4) box 30 in addition. The manufacturing method of the magnetic suspension (card) (8) container (4) box is: use plastic mold injection molding to produce an oblate container (4) box with an inner hollow diameter of 5-10cm and a height of 0.5-1.5cm, and the container (4) box A number of holes (5) with a diameter of 0.1 cm are placed on the outside of the lower part, and a magnetic sheet (7) with a magnetic force of 500-1500 Gauss is placed on the concave surface of the top of the container (4), and a magnetic sheet (7) of the same size is added on th...

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Abstract

The invention discloses application and a preparation method of sibutramine in preparation of an information therapeutic drug and a novel drug prepared by the preparation method. The information therapeutic drug is characterized in that the drug does not contact a human body directly during treatment, any substance ingredient of the drug can not be consumed, only drug information is utilized for physical treatment, but the chemical treatment effect can be achieved, a treatment window is enlarged by more than 1000 times, and the side effects of chemical treatment are avoided. After sibutramine is used as the information therapeutic drug, the contents of active ingredients are not changed, and sibutramine can also be used as a conventional preparation in the chemical treatment for secondary effective use.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a novel medicine of sibutramine. Background technique [0002] Compound Sibutramine hydrochloride, chemical name: N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N'-dimethylamine- Hydrated hydrochloride, chemical formula C 17 h 26 CLH·HCl·H 2 O, molecular weight 334.33. The properties are white crystalline powder, odorless and tasteless. Instantly soluble in water and alcohol. Sibutramine is a weight-loss drug, clinically used to treat obesity and the like. The pharmaceutical preparations of sibutramine include tablets, capsules and the like. The known sibutramine drugs are all used as chemotherapeutic drugs, which allow the compound sibutramine molecules to enter the human body (through oral absorption into the blood), distribute to various tissues, and produce sibutramine molecules through chemical reactions in the human body. pharmacological effects. In the prior art, si...

Claims

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Application Information

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IPC IPC(8): A61K31/137A61K47/02A61P3/04A61M37/00
Inventor 杨孟君杨哲
Owner 北京中卫神农慢性病医学研究院有限公司
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