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Preparation technology of polygonatum polysaccharide peptide

A polysaccharide polysaccharide and a preparation process technology are applied in the field of preparation technology of polysaccharide polysaccharide peptides, which can solve problems such as research difficulties, and achieve the effects of high purity, low production cost and good product quality.

Inactive Publication Date: 2012-10-31
SHAANXI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially in the fields of health care product development and drug development, most of the current research on polysaccharide peptides in this regard is focused on anti-tumor and improving immunity, but polysaccharide peptides, as a biologically active substance with a large molecular weight, are still under pharmacological research. There are many difficulties, so the use of polysaccharide peptides is still being developed as a health product for the time being.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] 1) Preparation:

[0021] Wash the Rhizome of Rhizoma Polygonatum, dry it at 80°C to constant weight, and crush it through a 60-mesh sieve. Weigh a certain amount of Rhizoma Polygonati dry powder in the Erlenmeyer flask of the reflux extractor, then add water with 10 times the weight of Rhizoma Rhizoma Polygonatum as the extraction solvent.

[0022] 2) Extraction and preliminary purification:

[0023] Move the Erlenmeyer flask to an electric furnace and heat it to 80°C, then move it to a constant temperature water bath, keep the extraction temperature at 80°C for hot water leaching for 2 hours, and extract twice; combine the extracts, concentrate under reduced pressure to 1 / 2 the total volume, add h 2 o 2 Make H 2 o 2 The final concentration is 1% (mass percentage), 60 ° C constant temperature decolorization for 30 minutes, then add the equivalent of 1 / 2 H 2 o 2 Amount (molar amount) of Na 2 SO 3 to remove hydrogen peroxide; then add an equal volume of 6% trichl...

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PUM

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Abstract

The invention discloses a preparation technology of polygonatum polysaccharide peptide. The polygonatum polysaccharide peptide is prepared from polygonatum by extraction, preliminary purification and separation and purification steps, and has the advantages of high purity, low generate cost, good product quality and three less wastes.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a preparation process of polygonatum polysaccharide peptide. Background technique [0002] Polysaccharide peptide is a kind of glycoprotein, which is a combination of polysaccharide and protein. It is a glucan containing protein. It generally contains a high proportion of polysaccharides. They are regarded as glycosaminoglycans with high molecular weight. composed of repeating units. Polysaccharide peptides have strong biological activity. Preliminary studies have shown that polysaccharide peptides can enhance the immune function of the body, have anti-tumor and anti-oxidative effects, but because the research on polysaccharide peptides of Polygonatum is still in its infancy, other biological functions have not been discovered. [0003] anti-aging effect [0004] Studies have found that Polygonatum polysaccharide and polysaccharide peptide mixture can reduce the production...

Claims

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Application Information

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IPC IPC(8): C08B37/02
Inventor 梁引库吴三桥徐仲阳张志健李新生张羽陈琛张辰露
Owner SHAANXI UNIV OF TECH
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