System for detecting electrical conductivity and pH (potential Of Hydrogen) during biological separation and purification process

Abstract

The invention relates to a system for detecting electrical conductivity and pH during the biological separation and purification process, and belongs to the field of bio-instruments. The system comprises an electric conductivity sensor, a pH sensor, a temperature sensor, a range switching circuit, an amplifying circuit, an excitation signal circuit, an analog-digital conversion circuit, a central processing unit, a display circuit, a keying circuit, an upper computer communication circuit and a power supply circuit, wherein the excitation signal circuit drives the electric conductivity sensor by an alternating current square wave excitation signal so as to overcome the polarization phenomenon of the electric conductance sensor; a weak voltage signal acquired by the pH sensor is amplified by a difference amplifier; a large capacitor is connected with an output part of the difference amplifier to effectively filter power frequency interference; the central processing unit is embedded into a temperature compensation program to compensate the error caused by temperature variation, so that the measuring accuracy and the detecting real-time performance are improved; and the upper computer circuit achieves the serial communication between a singlechip and a PC (personal computer).

Description

technical field [0001] The invention relates to a conductivity and pH detection system in the process of biological separation and purification, which belongs to the field of biological instruments. Background technique [0002] At present, conductivity meters and pH meters are widely used in the detection and analysis of related components such as biomedical pharmaceuticals. In the process of bioseparation and purification, the use of conductivity meters and pH meters to identify separated biological products is an essential link. Mass production of domestic bioseparation samples has begun, and there is a tendency to replace foreign products. However, most of the relevant equipment for bio-separation component detection is equipped with foreign products, such as GE's pH meter, conductivity meter, and ultraviolet spectroscopic detection equipment, which have the characteristics of small size and powerful functions, but are expensive. Most of the domestic products only have...

AI Technical Summary

Problems solved by technology

However, most of the relevant equipment for bio-separation component detection is equipped with foreign products, such as GE's pH meter, conductivity meter, and ultraviolet spectroscopic detection equipment, which have the characteristics of small size and powerful functions, but are expensive

Most domestic products only have a separate conductivity detection or pH detection function. Although there is a price advantage, there is no detection system for biological separation and purification, and it is impossible to measure multiple parameters such as conductivity and pH at the same time.

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