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Micro-fluidic paper chip for simultaneously detecting glucose, uric acid, triglycerides and cholesterols, and its manufacturing method

A microfluidic paper chip, triglyceride technology, applied in chemical instruments and methods, biological testing, material testing products, etc., can solve the problems of early detection and early diagnosis of unfavorable patients' conditions, high cost, time-consuming and laborious, etc. The effect of good specificity, intuitive phenomenon and simple operation

Inactive Publication Date: 2013-03-27
JIAMUSI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Large-scale biochemical analyzers can usually measure the blood concentration of the above substances at the same time, but it is time-consuming, laborious, costly, and relies on professional operators
Since diabetes, hyperlipidemia and gout are all chronic diseases that require long-term and frequent reexamination, the instrumental analysis method brings a lot of inconvenience to patients and is not conducive to early detection and early diagnosis of patients' conditions.
Although rapid and simple detection methods have been developed for glucose, triglycerides, cholesterol and uric acid in blood, there is no method that can simultaneously detect the above four substances with high throughput

Method used

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  • Micro-fluidic paper chip for simultaneously detecting glucose, uric acid, triglycerides and cholesterols, and its manufacturing method
  • Micro-fluidic paper chip for simultaneously detecting glucose, uric acid, triglycerides and cholesterols, and its manufacturing method
  • Micro-fluidic paper chip for simultaneously detecting glucose, uric acid, triglycerides and cholesterols, and its manufacturing method

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Embodiment 1

[0023] The specific preparation, assembly and testing process are as follows:

[0024] 1 the preparation process of photoetching microchannel among the present invention is as follows:

[0025] Brush SU-8 photoresist on TX609 paper, bake at 130°C for 10 minutes on a hot plate, cool at room temperature, cover with a mask with a designed pattern, expose to UV light for 14 seconds, bake at 130°C for 10 minutes at room temperature cool down. The photoresist in the area not covered by the channel undergoes a cross-linking reaction, and the photoresist in the area covered by the channel is removed by washing with acetone, and cleaned with an oxygen plasma cleaner for 3 seconds to restore the hydrophilicity of the channel area.

[0026] 2 The assembly process of the three-dimensional microfluidic paper chip in the present invention is as follows:

[0027] According to the design of the channel on the mask, holes are punched on the ordinary double-sided tape with glossy paper on bot...

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Abstract

The invention provides a micro-fluidic paper chip for simultaneously detecting glucose, uric acid, triglycerides and cholesterols, and its manufacturing method. The paper chip is a novel personalized diagnosis device, can rapidly, cheaply and simply detect multiple components without instrument equipment or professional people, can be operated by a patients or their families, and can momentarily and rapidly detect the concentrations of the glucose, the uric acid, the triglycerides and the cholesterols in blood.

Description

technical field [0001] The invention designs a three-dimensional microfluidic paper chip for simultaneous detection of glucose, uric acid, triglyceride and cholesterol. Background technique [0002] Blood biochemical indicators can reflect the health of the human body and are also an important basis for doctors to diagnose and treat. With the improvement of people's living standards, the incidence of diseases such as diabetes, hyperlipidemia and gout has increased significantly, seriously endangering human health. Therefore, the detection of glucose, triglyceride, cholesterol and uric acid in blood has become a routine detection item in hospitals. Large-scale biochemical analyzers can usually measure blood concentrations of the above substances at the same time, but they are time-consuming, laborious, costly, and rely on professional operators. Since diabetes, hyperlipidemia and gout are all chronic diseases that require long-term and frequent reexamination, the instrument...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/52B01L3/00
Inventor 邱洪斌张强郑佳昕王跃新祝丽玲
Owner JIAMUSI UNIVERSITY
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