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Cosmetic composition containing a cypress essential oil complex as an active ingredient for enhancing memory and improving cognitive dysfunction

A cosmetic composition, technology to improve cognition, applied in the field of cosmetic composition, to achieve the effect of excellent effect

Inactive Publication Date: 2013-03-27
SKINBIO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As mentioned above, in the existing natural plant-based compositions related to memory or dementia, since the compositions are mainly administered orally, there is inconvenience in daily life because of the need to take the medicine on time

Method used

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  • Cosmetic composition containing a cypress essential oil complex as an active ingredient for enhancing memory and improving cognitive dysfunction
  • Cosmetic composition containing a cypress essential oil complex as an active ingredient for enhancing memory and improving cognitive dysfunction
  • Cosmetic composition containing a cypress essential oil complex as an active ingredient for enhancing memory and improving cognitive dysfunction

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0044] Experimental example 1: Y-maze experiment

[0045] In order to confirm the effect of the essential oils obtained in the above examples on memory, the following experiments were carried out using the Y-maze method.

[0046] The Y-maze experimental device consists of three identical channels (6cm in width, 28cm in length, and 18cm in height), and each channel is arranged at a specified angle of 120° to each other. After the mouse was placed at the end of one passage, it was allowed to walk freely in the Y-maze for 8 min. Measure the number and sequence of entering each channel (arm) to evaluate the amount of spontaneous crossover action (spontaneous alteration, %). When entering the three channels in turn, define the spontaneous cross action volume as ABC, BCA, CAB, etc. Therefore, the % spontaneous cross action amount was calculated according to the following mathematical formula 1.

[0047] math formula 1

[0048] % Spontaneous cross action amount = (total action am...

experiment example 2

[0054] Experimental example 2: Water-maze experiment

[0055]The water maze test (Morris water-mazetest) is an experiment to confirm whether essential oils are helpful to the spatial cognition ability and short-term and long-term memory recovery (short and long-term memory recovery) of experimental animals. The experimental equipment consists of a circular sink (stainless steel, 120 cm in diameter, 45 cm in height) and an escape platform (platform: platform, 10 cm in diameter, 30 cm in height). The height of the water in the water tank (temperature 22°C±2°C) was 2cm higher than the stage, so that the body of the mouse was exposed to the water surface when standing on the escape stage. As far as the water maze experiment is concerned, since the experimental animals use the markers around the water tank to find the escape platform, the markers are kept stably at a prescribed level so that the surrounding environment during the experiment remains unchanged. When the experimental...

experiment example 3

[0062] Experimental Example 3: Passive Avoidance Experiment

[0063] Passive avoidance experiments were carried out in a device with the same structure of light box and dark box (width 25cm, length 20cm, height 20cm) connected by a truncated door. Light bulbs were installed in the light box, and stainless steel rods with a thickness of 2 mm were installed on the ground at a distance of 1 cm in the dark box so as to be able to impart electrical stimulation. After acclimatizing the experimental animals into the light box for 10 seconds, turn on the light bulb and open the truncation door for 20 seconds. If the experimental animal moves towards the dark box, the door will be automatically closed, and an electric shock (0.5mA, 5 seconds) will be applied (capture test: acquisition trial). After 24 hours, the experimental animals were put back into the bright box to perform the same procedure, whereby the step-through latency time (step-through latency) of the experimental animals ...

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Abstract

The present invention relates to a cosmetic composition containing cypress essential oil as a first essential oil and one or more second essential oils selected from the group consisting of pine needle essential oil, lavender essential oil, rosemary essential oil, red thyme essential oil, and bergamot essential oil. The composition has the effects of enhancing memory and reducing cognitive dysfunction by means of the fragrance thereof instead of via oral administration.

Description

technical field [0001] The present invention relates to a cosmetic composition, which comprises cypress essential oil and other active ingredients, which have the effect of improving memory and improving cognitive function. Background technique [0002] Dementia is generally a complex clinical syndrome that presents obvious damage to human cognitive function, intelligence, emotion and action changes. It is a kind of cerebral cortex dysfunction that produces memory, attention, language function, visual space ability, etc. There are great difficulties in the creation of daily and social life. Dementia is defined as impairment of more than one of the other cognitive functions, including memory, and memory loss alone does not qualify as dementia. [0003] The cause of dementia is Alzheimer's Disease or Parkinson's Disease as a degenerative brain disease, cerebral hemorrhage, hepatic encephalopathy as a metabolic disease, and Wilson's Disease , neurosyphilis as an infectious di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/14A61K36/53A61K36/15A61P25/00
CPCA61Q13/00A61K2800/10A61Q19/00A61K8/922A61Q5/02A61Q5/06A61Q15/00A61Q5/10A61Q19/10A61K9/0012A61K2800/5922A61P25/00A61P25/28A61P43/00
Inventor 汉守康
Owner SKINBIO CO LTD
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