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Traditional Chinese medicine composition for treating alzheimer diseases and preparation method of traditional Chinese medicine composition

A technology of Alzheimer's disease and composition, which is applied in the field of traditional Chinese medicine composition for the treatment of Alzheimer's disease, to achieve the effect of improving the level, improving learning and memory, and treating Alzheimer's disease

Active Publication Date: 2013-05-01
贵州神奇投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned drugs are mainly traditional Chinese medicine compositions, and products combining Chinese and Western medicines are relatively rare

Method used

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  • Traditional Chinese medicine composition for treating alzheimer diseases and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating alzheimer diseases and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating alzheimer diseases and preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] prescription:

[0137] Ginseng 25kg, Angelica 15kg, Polygonatum 15kg, Astragalus 15kg, Shouwu 15kg, Dodder 25kg, Panax notoginseng 13kg, Cinnamon 15kg, Lycium barbarum 15kg, Rehmannia 15kg, Chuanhu Cornus 15kg, Huai Yam 15kg, Ziheche 15kg, Polygala 15kg, Alisma orientalis 15kg, Shichangpu 15kg, Melatonin 15kg, Scorpion extract 15kg, Centipede extract 15kg, Dihydroartemisinin 15kg.

[0138] Preparation method:

[0139] (1) Dry the Zihe cart at a low temperature of 63°C and crush it into fine powder for later use;

[0140] (2) Crush ginseng, angelica, astragalus, panax notoginseng, cinnamon, and Cornus officinalis into fine powder for later use;

[0141] (3) Distill the volatile oil from Acorus calamus and collect the volatile oil for use;

[0142] (4) Add 8 times the amount of water to the residue after extracting volatile oil from Acorus calamus, Polygonatum, Shouwu, Cuscuta, Lycium barbarum, Rehmannia, Huai Yam, Polygala, Alisma for 3 times, each time 2h, decoct and filter. Com...

Embodiment 2

[0145] prescription:

[0146] Ginseng 20kg, Angelica 10kg, Polygonatum 10kg, Astragalus 10kg, Shouwu 10kg, Dodder 20kg, Panax notoginseng 10kg, Cinnamon 10kg, Lycium barbarum 10kg, Rehmannia 10kg, Chuan and Hubei Cornus 10kg, Huai Yam 10kg, Ziheche 10kg, Polygala 10kg, Alisma orientalis 10kg, Shichangpu 10kg, Melatonin 10, Scorpion extract 10kg, Centipede extract 10kg, Dihydroartemisinin 10kg.

[0147] Preparation method:

[0148] (1) Dry the Zihe cart at a low temperature of 62°C and crush it into fine powder for later use;

[0149] (2) Crush ginseng, angelica, astragalus, panax notoginseng, cinnamon, and Cornus officinalis into fine powder for later use;

[0150] (3) Distill the volatile oil from Acorus calamus and collect the volatile oil for use;

[0151] (4) The residue after extracting volatile oil from Acorus calamus and Polygonatum, Shouwu, Cuscuta, Lycium chinense, Rehmannia, Huai Yam, Polygala, Alisma, decocted 3 times with 8 times the amount of water, 1 hour each time, decoct...

Embodiment 3

[0154] prescription:

[0155] Ginseng 1kg, Angelica 5kg, Polygonatum 5kg, Astragalus 5kg, Shouwu 5kg, Cuscuta 5kg, Panax notoginseng 1kg, Cinnamon 5kg, Lycium barbarum 5kg, Rehmannia 5kg, Chuan and Hubei Dogwood 5kg, Huai Yam 5kg, Ziheche 5kg, Polygala 5kg, Alisma orientalis 5kg, Shichangpu 5kg, Melatonin 1kg, Scorpion extract 1kg, Centipede extract 1kg, Dihydroartemisinin 1kg.

[0156] Preparation method:

[0157] (1) Dry the Zihe cart at a low temperature of 60°C and crush it into fine powder for later use;

[0158] (2) Crush ginseng, angelica, astragalus, panax notoginseng, cinnamon, and Cornus officinalis into fine powder for later use;

[0159] (3) Distill the volatile oil from Acorus calamus and collect the volatile oil for use;

[0160] (4) Add 6 times the amount of water to the residue after extracting volatile oil from Acorus calamus, Polygonatum, Shouwu, Cuscuta, Lycium chinense, Rehmannia glutinosa, Chinese yam, Polygala, Alisma for 3 times, each time for 2 hours, decoct and ...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating alzheimer diseases and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is mainly prepared from the following traditional Chinese medicine: ginseng, angelica sinensis, rhizoma polygonati, astragalus mongholicus, fleece-flower root, semen cuscutae, radix notoginseng, cinnamon, wolfberry fruit, rehmannia glutinosa, cornus chinensis, Chinese yam and the like. The preparation method mainly comprises the following steps that (1) placenta hominis is dried at low temperature being 60 to 65 DEG C and is pulverized into fine powder for standby; (2) the ginseng, the angelica sinensis, the astragalus mongholicus, the radix notoginseng, the cinnamon and the cornus chinensis are pulverized into fine powder for standby; (3) rhizoma acori graminei is distilled for extracting volatile oil, the volatile oil is collected for standby; and (4) residues after the volatile oil extraction of the rhizoma acori graminei are decocted with the rhizoma polygonati, the fleece-flower root and the like for 2 to 3 times, the decoction liquid obtained in three times is combined, the filtering is carried out, the filter liquid is subjected to decompression and concentration into thick paste, and the like. The traditional Chinese medicine compatibility is reasonable, good treatment effects are realized on the alzheimer diseases, the effective rate is higher than 96 percent, the preparation method is scientific and effective, the medicine restriction or the toxic and side effect generation is avoided, and the effects of each traditional Chinese medicine can be fully realized.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating Alzheimer's disease and a preparation method thereof. Background technique [0002] At present, the prevalence of senile dementia in people over 65 years old worldwide is 10%, and up to 20% over 80 years old. The disease ranks fourth among the causes of death in developed countries, second only to heart disease, Alzheimer's disease and stroke. This disease has been listed as an important topic in geriatrics and geriatric psychiatry. The pathological changes of senile dementia are cerebral cortex atrophy, cortical nerve reduction, a large number of neurofibrillary tangles and senile plaques in the cerebral cortex and hippocampus. Clinically, it is characterized by the comprehensive decline of high-level neurological functions such as cognition, thinking, emotion, personality, behavior, and language in a state of clear consciousness. Typical symptoms include dementia, aphasia, ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P25/28A61K35/64A61K35/50A61K31/4045A61K31/357A61K35/646A61K35/648
Inventor 张芝庭张涛涛
Owner 贵州神奇投资有限公司
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