Multifunctional full-automatic cell and solution treating instrument

Abstract

The invention relates to a medical instrument, and especially relates to a multifunctional full-automatic cell and solution treating instrument. The instrument comprises an ultrafilter, a liquid storage container, a peristaltic pump, an electromagnetic valve mixer and a temperature controller, wherein special components in a cell suspension or solution are displaced by a method of instillation combined with ultrafiltration and dialysis, or the cell suspension or solution is diluted and concentrated to desired final volume through accurate control. The multifunctional full-automatic cell and solution treating instrument effectively overcomes the shortages of the existing related treatment methods in the aspects of causing damage of cells, possibly causing cell pollution, taking long time, and low efficiency and the like; and the multifunctional full-automatic cell and solution treating instrument is capable of adding or removing a low-temperature protector quickly and steadily without pollution, and also capable of controlling the volumes and the temperatures of the cell suspension and the solution quite accurately and reducing various cell damages possibly caused in the treatment process. The multifunctional full-automatic cell and solution treating instrument has the advantages of small volume, simple structure, little time consumed and high controllability, and is convenient to operate.

Description

technical field [0001] The present invention relates to a medical instrument, in particular to a multi-functional automatic cell and solution processing instrument for replacing specific components in cell suspension or diluting and concentrating cell suspension by means of perfusion, ultrafiltration and dialysis Background technique [0002] During cryopreservation or cryopreservation of cells, in order to reduce cryogenic damage, it is often necessary to add a specific type and concentration of a cryoprotectant to the preserved cell suspension. For example, the commonly used cryoprotectant for preserving human hematopoietic stem cells is dimethyl sulfoxide (DMSO), while the commonly used for preserving human red blood cells is glycerol. In the process of treatment, if the cell suspension and the cryoprotectant in the cells are not removed in advance, but the cell suspension containing the cryoprotectant is directly injected into the human body, the blood in the body will r...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a method that effectively overcomes the shortcomings of existing related treatment methods in terms of cell damage, possible cell contamination, time-consuming, low efficiency, etc., can quickly and smoothly add or remove cryoprotectants without pollution, and can More precisely control the addition or removal rate and the volume and temperature of the cell suspension to reduce various cell damages that may be caused during the treatment process. A multi-functional automatic cell and solution processor for adding and removing cryoprotectants in the cell suspension

Images