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Space-induced efficient cordyceps militaris and application thereof as well as preparation method of capsule preparation of space-induced efficient cordyceps militaris

A technology of space mutagenesis and Cordyceps militaris, which is applied in the field of microorganisms, can solve the problems of small strain variation, inability to breed, and instability of mutant strains, and achieve the effects of increasing content, ensuring stability, and increasing yield

Active Publication Date: 2013-08-28
神舟太空集团(深圳)高科技有限公司
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Problems solved by technology

However, the existing methods for routine mutagenesis of bacterial strains are inefficient, and a large number of original strains need to be mutagenized, and the variation range of the strains screened out by conventional mutagenesis is small, so it is difficult to increase the target product Cordyceps sinensis in the fermentation product on a large scale. polysaccharide yield
In addition, conventional mutagenesis will have a "phenotype delay" effect, that is, the contemporary strains do not show the advantages of increased yield, cannot be selected in time, and are easily discarded, and are prone to "genetic segregation", that is, the mutant strains do not Stable and cannot be used for long-term large-scale production of Cordyceps militaris

Method used

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  • Space-induced efficient cordyceps militaris and application thereof as well as preparation method of capsule preparation of space-induced efficient cordyceps militaris
  • Space-induced efficient cordyceps militaris and application thereof as well as preparation method of capsule preparation of space-induced efficient cordyceps militaris
  • Space-induced efficient cordyceps militaris and application thereof as well as preparation method of capsule preparation of space-induced efficient cordyceps militaris

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Embodiment Construction

[0050] The present invention will be described in detail below in combination with specific embodiments.

[0051] A space mutagenesis efficient Cordyceps militaris described in the present invention ( Cordyceps militaris ) S7-T9 was deposited on May 19, 2011 at the General Microbiology Center of China Committee for the Collection of Microbial Cultures. The address is No. 3, No. 1, Beichen West Road, Chaoyang District, Beijing, Institute of Microbiology, Chinese Academy of Sciences, and the deposit number is CGMCC No. .4879.

[0052] The experimental methods in the following content, unless otherwise specified, are conventional methods; the experimental materials used in the following examples, unless otherwise specified, are conventional biochemical reagents.

[0053] 1. Screening and training:

[0054] A strain of Cordyceps militaris described in the present invention ( Cordyceps militaris ), is a ground control strain S7-D9 (preservation number: CGMCC 5.888) that uses the S...

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Abstract

The invention relates to space-induced efficient cordyceps militaris and application thereof as well as a preparation method of a capsule preparation of the space-induced efficient cordyceps militaris. A conventional induced mutation technology is used for selecting cordyceps militaris which is suitable for fermentation production is low in efficiency and small in variation range, needs lots of original strains to mutate, and difficultly improves the yield of the target product cordyceps polysaccharide in a fermentation product on a large scale. The invention provides cordyceps militaris (Cordyceps militaris) S7-T9 which can be applied to preparation of a medicine and a health-care product which can resist oxidization and improve sleeping quality. According to the cordyceps militaris, the hereditary characters of the strain are changed from genes; 'phenomic lag' and 'genetic separation phenomenon' caused by common mutation are compensated; a high-quality strain can be rapidly obtained; the stability of the strain is ensured; the yield of the strain is improved on a large scale; the content of cordyceps polysaccharide in the cordyceps militaris is greatly improved; and the space-induced efficient cordyceps militaris can be used for large-scale production.

Description

technical field [0001] The invention relates to the technical field of microbes, in particular to a high-efficiency Cordyceps militaris for space mutagenesis, its application and a method for preparing capsule preparations. Background technique [0002] Cordyceps militaris, referred to as Cordyceps militaris or Cordyceps militaris, is a medicinal fungus belonging to the Ascomycetes class Cordyceps. Cordyceps militaris is not only rich in protein and amino acid, but also contains more than 30 kinds of trace elements needed by the human body. It is a top-notch nourishing product. Modern medical research has proved that Cordyceps contains Cordyceps polysaccharides, cordycepin, cordycepic acid, SOD (superoxide dismutase) and rich selenium (Se) and other nutrients, which have hypnotic and sedative properties, liver and kidney benefits, tonifying deficiency, preventing Cancer, anti-cancer, hemostasis, phlegm, asthma and other functions. [0003] Cordyceps polysaccharide is one ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01H15/00A01G1/04A23L1/28A61K36/068A61P39/06A61P25/20
Inventor 赵恒
Owner 神舟太空集团(深圳)高科技有限公司
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