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Natural medicine composition

A technology of natural medicines and compositions, applied in drug combinations, antitumor drugs, pharmaceutical formulations, etc., can solve the problems of patients with dehydration, acid-base balance disorders, malnutrition, etc., and achieve increased inhibitory effect, enhanced inhibitory effect, and good side effects. Effect

Inactive Publication Date: 2013-09-18
石强
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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural medicine composition

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Embodiment approach

[0036] The first step: preparation of various extracts

[0037] (1) Preparation of the concentrated extract of Schisandra yam decoction

[0038] Take schisandra chinensis and yam according to the compatibility ratio of 1-4:1, soak in distilled water for 1 hour, heat and decoct for 1 hour, filter with silk cloth, save the filtrate, add distilled water to the medicinal residue, soak, decoct, and filter in the same way, and mix the two filtrates , concentrated by heating to a small volume, filtered by an ultrafiltration membrane, and dried under reduced pressure at 70°C to obtain a brown-yellow powder.

[0039] (2) Preparation of Schisandra polysaccharide

[0040] Take the dried fruit of Schisandra chinensis, crush and sieve, degrease with absolute ethanol Soxhlet reflux, dry, add water to extract at 90°C, filter, extract under reduced pressure, analyze with 95% ethanol, centrifuge to collect the precipitate, and separate the precipitate with acetone and ether Wash with absolut...

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Abstract

The invention relates to a natural medicine composition. The natural medicine composition is composed of schisandra chinensis-Chinese yam decoction concentration extract, schisandra chinensis polysaccharides, Chinese yam ethanol extract and Chinese yam polysaccharides in a ratio of (2 to 4): (2 to 9): (1 to 4): (5 to 8). The composition has a great curative effect on cancer chemotherapy associated diarrhea and can act a synergistic effect on cancer chemotherapy simultaneously.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of Schisandra yam decoction concentrated extract, Schisandra polysaccharide, yam ethanol extract and yam polysaccharide, the preparation method of the natural medicine composition And the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, whether they are used alone or in combination, they will cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P35/00A61P1/12A61K31/715
Inventor 石强
Owner 石强
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