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Natural pharmaceutical composition

A technology of natural medicines and compositions, applied in drug combinations, antitumor drugs, pharmaceutical formulations, etc.

Inactive Publication Date: 2013-09-18
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of the concentrated extract of cardamom scutellaria baicalensis decoction

[0037] According to the compatibility ratio of 1-4:1, take cardamom and scutellaria baicalensis, soak in distilled water, heat and decoct, filter with silk cloth, add distilled water to the medicinal residue, soak, decoct and filter in the same way, mix the two filtrates, heat and concentrate, Ultrafiltration membrane filtration, drying under reduced pressure at 70°C.

[0038] (2) Preparation of ethyl acetate extract of cardamom

[0039] Take Scutellaria baicalensis coarse powder, reflux and extract with 55% ethanol for several times, filter, combine the filtrates, recover ethanol, concentrate and dry to obtain the product.

[0040] (3) Preparation of total flavonoids from Scutellaria baicalensis

[0041] Weigh the crude Scutellaria baicalensis powder, put it in a round bottom flask, use 55% ethanol with a solid-liquid r...

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Abstract

The invention relates to a natural pharmaceutical composition. The natural pharmaceutical composition comprises a katsumade galangal seed and baical skullcap root water decoction concentrated extract, a katsumade galangal seed ethyl acetate extract, total flavonoids of baical skullcap root and baicalin according to the proportion of (2-4): (3-8): (3-9): (1-4), and the composition has an excellent curative effect against diarrhea which is related to cancer chemotherapy and can simultaneously realize a synergistic action against the cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of concentrated extract of Scutellaria baicalensis decoction, ethyl acetate extract of Cardamomum baicalensis, total flavonoids of Scutellaria baicalensis and baicalin. The preparation method of the composition and the use of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemothera...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P35/00A61P1/12A61K31/7048
Inventor 石强
Owner 石强
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