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Novel microporous medical hemostatic material and preparation method thereof

A hemostatic material and microporous technology, applied in the field of biomedical hemostatic materials, can solve the problems of incomplete hemostasis and limited wide application, and achieve the effect of enhancing hemostatic effect, not easy to decompose, and stable decomposition

Active Publication Date: 2013-10-16
GUANGXI XINYE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it only achieves physical hemostasis on the wound surface by virtue of its porous structure and rapid water absorption, so the hemostasis is not complete, which limits its wide application in clinical practice.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] A novel microporous medical hemostatic material, the novel microporous medical hemostatic material is made up of the following raw materials in percentage by weight: microporous potato starch 80%, Chinese medicine extract 20%, the above-mentioned microporous potato starch and Chinese medicine extract Add it into a mixer, mix evenly, and obtain a novel microporous medical hemostatic material after sterilization.

[0070] The traditional Chinese medicine extract is obtained by boiling and extracting Sanqi with purified water, filtering the filtrate, concentrating the filtrate and drying the powder.

[0071] The preparation method of described microporous potato starch comprises the following steps:

[0072] Step A, add distilled water in 100g potato starch, be made into the starch milk that mass percentage concentration is 16%, then add 2g sodium chloride, stir;

[0073] Step B, adding 1% sodium trimetaphosphate relative to the quality of potato starch, adjusting the pH ...

Embodiment 2

[0079] A novel microporous medical hemostatic material, the novel microporous medical hemostatic material is composed of the following raw materials in weight percentage: microporous tapioca starch 95%, Chinese medicine extract 5%, the above-mentioned microporous tapioca starch and Chinese medicine extract Add it into a mixer, mix evenly, and obtain a novel microporous medical hemostatic material after sterilization.

[0080] The traditional Chinese medicine extract is composed of the following raw materials in parts by weight: 10 parts of Panax notoginseng extract, 30 parts of Burnet eucalyptus extract, and 20 parts of Eclipta chinensis extract. The extract of notoginseng is obtained by boiling and extracting notoginseng with purified water, filtering the filtrate, concentrating the filtrate and drying the powder. The Burnet extract is a powder obtained by boiling Burnet with purified water, filtering the filtrate, concentrating the filtrate, and drying. The extract of Eclip...

Embodiment 3

[0089] A novel microporous medical hemostatic material, the novel microporous medical hemostatic material is made up of the following raw materials in percentage by weight: microporous sweet potato starch 25%, Chinese medicine extract 75%, the above-mentioned microporous sweet potato starch and Chinese medicine extract Add it into a mixer, mix evenly, and obtain a novel microporous medical hemostatic material after sterilization.

[0090] The traditional Chinese medicine extract is composed of the following raw materials in parts by weight: 30 parts of Eclipta chinensis extract, 30 parts of Siberia clover leaf extract, 30 parts of lotus pod extract, and 20 parts of Agrimony extract. The above extract is obtained by boiling and extracting the raw materials of the traditional Chinese medicine with purified water, filtering the filtrate, concentrating the filtrate and drying the obtained powder.

[0091] The preparation method of described microporous sweet potato starch comprise...

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Abstract

The invention relates to a biomedical hemostatic material, in particular to a novel microporous medical hemostatic material and a preparation method thereof. The hemostatic material consists of microporous starch and a traditional Chinese medicine extractive, wherein the microporous starch is one of or a mixture of more than two of microporous potato starch, cassava starch, sweet potato starch, corn starch, barley starch, wheat starch, rice starch and the like, and the traditional Chinese medicine extractive is one of or a mixture of more than two of a radix notoginseng extractive, a radix sanguisorbae extractive, an eclipta extractive, a madder extractive, a cacumen biotae extractive, a lotus seedpod extractive, a nodus nelumbinis rhizomatis extractive, a sophora flower extractive, a pollen typhae extractive, a rhubarb extractive, a hairyvein agrimony extractive and the like. The microporous starch has a function of a molecular sieve, and can quickly absorb moisture in blood, form instant gel, and mechanically block off a blood vessel crevasse; a physical barrier can isolate a wound, and exerts an anti-adhesion function; and the traditional Chinese medicine extractive has hemostatic, antiphlogistic, antibacterial, antalgic, convergent, and blood coagulation system activation functions.

Description

technical field [0001] The invention relates to the technical field of biomedical hemostatic materials, in particular to a novel microporous medical hemostatic material and a preparation method thereof. Background technique [0002] Blood is an important link in the operation of various departments in the hospital, and plays a considerable role in the success of the operation and the safety of the patient. The normal hemostasis mechanism mainly includes three aspects: the contraction of small blood vessels, the activation of platelets and the activation of the coagulation system. Among them, the contraction of small blood vessels is the earliest response to hemostasis after trauma. After the blood vessels are damaged, the smooth muscles of the blood vessels constrict the blood vessels and slow down the blood flow through axon reflex, which is beneficial to blood coagulation and hemostasis. Platelets have the physiological function of adhering to the surface of wounds and fo...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61K36/88A61K36/74A61K36/739A61K36/73A61K36/708A61K36/62A61K36/489A61K36/28A61K36/258A61P7/04
Inventor 梁奕福
Owner GUANGXI XINYE BIOLOGICAL TECH
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