Novel microporous medical hemostatic material and preparation method thereof

A hemostatic material and microporous technology, applied in the field of biomedical hemostatic materials, can solve the problems of incomplete hemostasis and limited wide application, and achieve the effect of enhancing hemostatic effect, not easy to decompose, and stable decomposition

Active Publication Date: 2013-10-16
GUANGXI XINYE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it only achieves physical hemostasis on the wound surface by virtue of its porous structure and rapi

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0068] Example 1.

[0069] A new type of microporous medical hemostatic material, the new type of microporous medical hemostatic material is composed of the following weight percentages of raw materials: 80% of microporous potato starch, 20% of Chinese medicine extract, and the above amount of microporous potato starch and Chinese medicine extract It is added into a mixer and mixed evenly, and a new type of microporous medical hemostatic material is obtained after sterilization.

[0070] The traditional Chinese medicine extract is a powder obtained by boiling Panax notoginseng with purified water, filtering the filtrate, and concentrating and drying the filtrate.

[0071] The preparation method of the microporous potato starch includes the following steps:

[0072] Step A: Add distilled water to 100 g of potato starch to prepare a starch milk with a mass percentage concentration of 16%, then add 2 g of sodium chloride, and stir evenly;

[0073] Step B: Add 1% sodium trimetaphosphate re...

Example Embodiment

[0078] Example 2.

[0079] A new type of microporous medical hemostatic material, the new type of microporous medical hemostatic material is composed of the following weight percentages of raw materials: 95% of microporous tapioca starch, 5% of Chinese medicine extract, the above amount of microporous cassava starch and Chinese medicine extract It is added into a mixer and mixed evenly, and a new type of microporous medical hemostatic material is obtained after sterilization.

[0080] The Chinese medicine extract is composed of the following raw materials in parts by weight: 10 parts of Panax notoginseng extract, 30 parts of Sanyu extract, and 20 parts of Eclipta prostrata extract. Panax notoginseng extract is a powder obtained by boiling Panax notoginseng with purified water, filtering the filtrate, and concentrating and drying the filtrate. Sanyu extract is a powder obtained by boiling Sanyu with purified water, filtering the filtrate, and concentrating and drying the filtrate....

Example Embodiment

[0088] Example 3.

[0089] A new type of microporous medical hemostatic material, the new type of microporous medical hemostatic material is composed of the following weight percentage of raw materials: 25% of microporous sweet potato starch, 75% of Chinese medicine extract, the above amount of microporous sweet potato starch and Chinese medicine extract It is added into a mixer and mixed evenly, and a new type of microporous medical hemostatic material is obtained after sterilization.

[0090] The traditional Chinese medicine extract is composed of the following raw materials in parts by weight: 30 parts of Eclipta prostrata extract, 30 parts of Platycladus orientalis extract, 30 parts of lotus tree extract, and 20 parts of Agrimony extract. The above extract is a powder obtained by boiling the raw materials of traditional Chinese medicine with purified water, filtering the filtrate, and concentrating and drying the filtrate.

[0091] The preparation method of the microporous swee...

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Abstract

The invention relates to a biomedical hemostatic material, in particular to a novel microporous medical hemostatic material and a preparation method thereof. The hemostatic material consists of microporous starch and a traditional Chinese medicine extractive, wherein the microporous starch is one of or a mixture of more than two of microporous potato starch, cassava starch, sweet potato starch, corn starch, barley starch, wheat starch, rice starch and the like, and the traditional Chinese medicine extractive is one of or a mixture of more than two of a radix notoginseng extractive, a radix sanguisorbae extractive, an eclipta extractive, a madder extractive, a cacumen biotae extractive, a lotus seedpod extractive, a nodus nelumbinis rhizomatis extractive, a sophora flower extractive, a pollen typhae extractive, a rhubarb extractive, a hairyvein agrimony extractive and the like. The microporous starch has a function of a molecular sieve, and can quickly absorb moisture in blood, form instant gel, and mechanically block off a blood vessel crevasse; a physical barrier can isolate a wound, and exerts an anti-adhesion function; and the traditional Chinese medicine extractive has hemostatic, antiphlogistic, antibacterial, antalgic, convergent, and blood coagulation system activation functions.

Description

technical field [0001] The invention relates to the technical field of biomedical hemostatic materials, in particular to a novel microporous medical hemostatic material and a preparation method thereof. Background technique [0002] Blood is an important link in the operation of various departments in the hospital, and plays a considerable role in the success of the operation and the safety of the patient. The normal hemostasis mechanism mainly includes three aspects: the contraction of small blood vessels, the activation of platelets and the activation of the coagulation system. Among them, the contraction of small blood vessels is the earliest response to hemostasis after trauma. After the blood vessels are damaged, the smooth muscles of the blood vessels constrict the blood vessels and slow down the blood flow through axon reflex, which is beneficial to blood coagulation and hemostasis. Platelets have the physiological function of adhering to the surface of wounds and fo...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61K36/88A61K36/74A61K36/739A61K36/73A61K36/708A61K36/62A61K36/489A61K36/28A61K36/258A61P7/04
Inventor 梁奕福
Owner GUANGXI XINYE BIOLOGICAL TECH
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