Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Chinese herbal compound extract with effect of resisting proliferation of mammary gland, and preparation method thereof

A technique for mammary gland hyperplasia and extract, which is applied in the field of traditional Chinese medicine compound extract with anti-mammary gland hyperplasia effect and its preparation, can solve the problems of obvious side effects, large wound area, high cost, etc., and achieves non-toxic side effects, stable quality, and convenient use Effect

Inactive Publication Date: 2013-10-23
雷允上药业有限公司
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Whether it is surgical resection or drug treatment, there are disadvantages such as high cost, obvious side effects, large trauma, and easy recurrence after surgery or drug withdrawal.
Therefore Western medicine still does not have ideal solution approach and treatment method to this disease

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chinese herbal compound extract with effect of resisting proliferation of mammary gland, and preparation method thereof
  • Chinese herbal compound extract with effect of resisting proliferation of mammary gland, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A preparation method of a compound Chinese medicine extract with anti-mammary gland hyperplasia, comprising the following steps:

[0039] a. Take 12.5 parts of Bupleurum bupleurum, 8.34 parts of wine-roasted rhubarb, 8.34 parts of Fritillaria japonicus, 12.5 parts of white peony root, 8.34 parts of fried wangbuliuxing and pass through a 60-mesh sieve, add 70% ethanol to reflux and extract 3 times, After 3 hours, filter, concentrate the filtrate until it has no alcohol smell, then dilute with water to 0.25g to 4g crude drug / mL liquid medicine;

[0040] b. Take 12.5 parts Cyperus Cyperi, 8.34 parts Rhizoma Chuanxiong, 8.34 parts Curcuma, 12.5 parts Angelica, and 8.34 parts Qingpi, mix them in proportion, add water 12 times the total weight of medicinal materials, and extract by steam distillation to obtain volatile oil components; filter the extract , the filtrate was concentrated until the crude drug content was 0.75g / ml, then added ethanol until the alcohol concentratio...

Embodiment 2

[0047] The Chinese medicine compound extract with anti-mammary gland hyperplasia effect of the present invention, it is prepared by following method:

[0048] a. Take 20 parts of Bupleurum bupleurum, 15 parts of wine-roasted rhubarb, 15 parts of Fritillaria japonicus, 20 parts of white peony root, and 15 parts of fried Wangbuliuxing, add 8, 10 and 12 times the amount of water to extract 3 times, each time After 2 hours, the extract was filtered, and the filtrate was concentrated to 0.25g to 4g crude drug / mL liquid;

[0049] b. Take 15 parts of Ligusticum chuanxiong, 15 parts of curcuma, 20 parts of angelica, and 15 parts of fried green skin and extract them by steam distillation. The obtained volatile oil is dissolved in 80ml of water with 8g of β-cyclodextrin per milliliter of volatile oil, and heated at 60°C. Stir for 1 hour for inclusion; filter the extract, add ethanol to make the concentration of ethanol 80% alcohol, place the precipitate, filter, concentrate the filtrate...

Embodiment 3

[0055] The Chinese medicine compound extract with anti-mammary gland hyperplasia effect of the present invention, it is prepared by following method:

[0056] a. Take 10 parts of Bupleurum bupleurum, 5 parts of wine-roasted rhubarb, 5 parts of Zhe Fritillaria, 10 parts of white peony, and 5 parts of fried Wangbuliuxing, add 10 times the amount, and extract with 70% ethanol for 3 times, each time 2 hour, the extract was filtered, and the filtrate was concentrated to 0.25g to 4g crude drug / mL medicinal solution;

[0057] b. Take 5 parts of Rhizoma Chuanxiong, 5 parts of Curcuma, 10 parts of Angelica sinensis, and 5 parts of fried green bark, and use steam distillation to extract the obtained volatile oil. Use 8g of β-cyclodextrin per ml of volatile oil, dissolve it in 80ml of water, and heat it at 60°C Stir for 1 hour for inclusion; filter the extract, add ethanol to make the concentration of ethanol 60% alcohol, place the precipitate, filter, concentrate the filtrate until ther...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese herbal compound extract with an effect of resisting proliferation of mammary gland, and a preparation method thereof. The Chinese herbal compound extract is prepared by the following raw materials by weight: 10-20 parts of radix bupleuri, 10-20 parts of rhizoma cyperi, 5-15 parts of rheum officinale, 5-15 parts of pericarpium citri reticulatae viride, 5-15 parts of rhizoma chuanxiong, 5-15 parts of rhizoma curcumae, 5-15 parts of fritillary bulb, 10-20 parts of angelica sinensis, 10-20 parts of white peony root, 5-15 parts of ground beetle and 5-15 parts of cowherb seed. The Chinese herbal compound extract is prepared by a scientific formula, treats based on syndrome differentiation according to the theory of traditional Chinese medicine. Active components and an optimum preparation process are screened out by adopting a modern chemical component extraction separation and a pharmacological experiment tracking method. Pharmacological experiments show that the Chinese herbal compound extract provided by the invention has very good effect for treating the proliferation of the mammary gland, and has no toxic and side effect. The preparation method provided by the invention is stable in process and good in repeatability. The prepared extract is stable in quality. A plurality of oral drug preparations can be prepared and the oral drug preparations are convenient for clinic use.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound, in particular to a traditional Chinese medicine compound extract with anti-mammary gland hyperplasia effect and a preparation method thereof. Background technique [0002] Hyperplasia of mammary glands is a common women's surgical disease. Its incidence rate accounts for 75% of all breast diseases and 40% of women of childbearing age. The possibility of canceration accounts for about 2 to 4%. Therefore, it is of great significance to actively treat hyperplasia of mammary glands, improve women's health, and reduce the rate of canceration. [0003] Modern medicine believes that the occurrence of mammary gland hyperplasia is due to endocrine dysfunction and ovarian dysfunction, resulting in increased estrogen levels or activity enhancement in the body and decreased progesterone levels. For patients with severe breast hyperplasia pain or obvious local nodules and obvious tenderness, hormon...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K47/48A61P15/14A61K35/64A61K47/61
Inventor 狄留庆许惠琴赵晓莉严燕青贡磊李全叶华
Owner 雷允上药业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com