Compound type biological tissue and cell chip

A cell chip and biological tissue technology, applied in bioreactor/fermenter combination, microbial library, biomass post-processing, etc., can solve problems such as difficult chip experiment results, difficult quality control, expensive antibody consumption, etc., to increase research The effect of obtaining information, expanding the scope of research, and good scientific thinking

Inactive Publication Date: 2014-01-15
毛静涛 +1
View PDF0 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention mainly solves three problems: 1. The single-level research of gene chips, protein chips, cell chips, and tissue chips in biochips has great limitations. There are many uncontrollable factors in experimental conditions, difficult quality control, and waste of time and experimental reagents. , consumables, etc. 2. It is very difficult to compare the experimental results of c

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0009] The first is to design composite biological tissues and cell chips, determine the types of composite biological tissues and cell chips according to different purposes, determine the number of cases (specimens), and treat the samples; secondly, the tissue and cell samples For the treatment, the cell specimens were first centrifuged at 3000 rpm, washed three times, and then, a variety of traditional formaldehyde, isotonic neutral formaldehyde, acetone and other tissue fixatives were selected, and tested according to different ratios. Finally, isotonic neutral fixatives were selected. Formaldehyde is used as a fixative to fix cell specimens for more than 8 hours, and then dehydrated, embedded, sectioned, stained, and diagnosed; the tissue processing is relatively easy, just follow the traditional method of dehydration and embedding. Third, make a blank wax block mold, roughen the surface of the glass slide carrier, and carry out re-drawing, embedding, and slicing of composi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a compound type biological tissue and cell chip, relating to the subjects such as molecular biology, clinical medicine, veterinary medicine, zoology, medicinal form teaching and the like. At present, single tissue chip and cell chip are under great restriction in experimental study and clinical diagnosis work, comparative study on the tissue and cell can not be implemented, the internal structure of the cell can not be observed, and the expensive antibody, time and the like are wasted; the problems are solved perfectly by adopting the compound type biological tissue and cell chip. Tissue and cell specimens are fixed, dehydrated and embedded into tissue and cell wax blocks according to a tissue specimen treatment mode; then, the materials are drawn for the second time according to the subject design, the tissue and cell specimen columns are arrayed on the same carrier before being embedded and sliced, and subsequent experiments such as immunohistochemistry and the like are carried out synchronously. The compound type biological tissue and cell chip is mainly used for performing comparative study on the tissue and cell level in a scientific research activity, observing the internal cell organelle structure of the cell and carrying out batch detection diagnosis on the clinical cytology specimens, thereby having great significance in scientific research and bringing good social and economic benefits.

Description

technical field [0001] The patented composite biological tissue and cell chip of the present invention relate to molecular biology, cytological diagnosis in clinical medicine, veterinary medicine, zoology, medical morphology teaching and other disciplines. Background technique [0002] Biochip introduces the concept of chip in electronic technology into the field of biotechnology. It arranges biological materials (which can be genes, proteins, cells, tissues) in a certain number and order on glass slides, plastics, etc. according to different requirements. Carriers such as agar are provided for research in the fields of medicine and biology. At present, single gene chips, protein chips, cell chips, and tissue chips have relatively mature technologies, products, and markets. According to new research results, there are no reports of composite biological tissue and cell chips at home and abroad, and they are the first at home and abroad. [0003] Composite biological tissue a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C12M1/00C40B40/02
CPCG01N1/28G01N1/34
Inventor 毛静涛
Owner 毛静涛
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap