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A traditional Chinese medicine composition for treating fatty liver and its application

A composition and technology of traditional Chinese medicine, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of liver toxicity, aggravated liver function damage, unsatisfactory short-term curative effect, etc., achieve and reverse the fatty degeneration of liver tissue and inflammation, Lower content, good anti-lipid peroxidation effect

Inactive Publication Date: 2015-12-30
上海市浦东新区传染病医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinical practice has proved that the short-term efficacy of such drugs is not ideal, and long-term use has liver toxicity, which can aggravate liver function damage.

Method used

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  • A traditional Chinese medicine composition for treating fatty liver and its application
  • A traditional Chinese medicine composition for treating fatty liver and its application
  • A traditional Chinese medicine composition for treating fatty liver and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1 Granules

[0029] Weigh raw materials: Atractylodes atractylodes 6 grams, Atractylodes macrocephala 10 grams, lotus leaf 10 grams, cassia seed 10 grams, chrysanthemum 10 grams, Puhuang 6 grams, Schisandra chinensis 6 grams.

[0030] Add 10 times the amount of water to the above crude drug, heat and reflux for extraction for 2 hours, and filter; then add 8 times the amount of water, heat and reflux for 1 hour, and filter; discard the drug residues, and combine the two extracts. Concentrate and dry to obtain a dry extract; add appropriate amount of auxiliary materials to prepare granules, pack in bags, 14 grams per bag, orally 3 times a day, 1 bag each time.

Embodiment 2

[0031] Embodiment 2 Granules

[0032] Weigh raw materials: Atractylodes atractylodes 6 grams, Atractylodes macrocephala 6 grams, lotus leaf 3 grams, cassia seed 9 grams, chrysanthemum 5 grams, Puhuang 5 grams, schisandra 2 grams.

[0033] Add 10 times the amount of water to the above crude drug, heat and reflux for extraction for 2 hours, and filter; then add 8 times the amount of water, heat and reflux for 1 hour, and filter; discard the drug residues, and combine the two extracts. Concentrate and dry to obtain a dry extract; add appropriate amount of auxiliary materials to prepare granules, pack in bags, 8 grams per bag, orally 3 times a day, 1 bag each time.

Embodiment 3

[0034] Embodiment 3 granules

[0035] Weigh raw materials: Atractylodes atractylodes 12 grams, Atractylodes macrocephala 12 grams, lotus leaf 10 grams, cassia seed 15 grams, chrysanthemum 10 grams, Puhuang 10 grams, Schisandra chinensis 6 grams.

[0036] Add 10 times the amount of water to the above crude drug, heat and reflux for extraction for 2 hours, and filter; then add 8 times the amount of water, heat and reflux for 1 hour, and filter; discard the drug residues, and combine the two extracts. Concentrate and dry to obtain a dry extract; add appropriate amount of auxiliary materials to prepare granules, pack in bags, 18 grams per bag, orally 3 times a day, 1 bag each time.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating fatty liver. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 6-12 parts of rhizoma atractylodis, 6-12 parts of atractylodes macrocephala, 3-10 parts of lotus leaves, 9-15 parts of semen cassiae, 5-10 parts of chrysanthemum, 5-10 parts of typhae pollen and 2-6 parts of fructus schizandrae. Furthermore, the invention discloses the application of the traditional Chinese medicine composition. An experiment shows that the traditional Chinese medicine composition has good therapeutic effects of reducing fat deposition in the liver, relieving hepatocellular fatty degeneration and alleviating hepatocellular injury, has a good effect of resisting lipid peroxidation and has important significance for the treatment of the fatty liver and an application value.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicines and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating fatty liver and its application. Background technique: [0002] Fatty liver is a disease of lipid metabolism disorder in which fatty degeneration occurs in liver cells. When the lipid in the liver cells exceeds 5% of the wet weight of the liver, or when more than 30% of the liver parenchyma is fatty in histology, it is fat liver. In recent years, with the improvement of people's living standards and the increase of the aging population, excessive calorie intake in the diet, while the amount of exercise continues to decrease, the excess calories are converted and stored in the liver, adipose tissue and other organs, resulting in the incidence of fatty liver year by year increase, and the age of onset tends to be younger. Survey results in some areas of m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61P1/16A61P39/06
Inventor 成扬陈建杰候天禄龚亚华张盛杰孙莲娜陆卫英杜秀萍滕惠琴平键陈高峰奚骏薛建华齐艳艳
Owner 上海市浦东新区传染病医院
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