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Pharmaceutical composition for treating duck and goose flavivirus infection and preparation method thereof

A goose yellow virus infection and composition technology, which is applied in the field of veterinary medicines, can solve the problems of adverse effects on human health, easy generation of drug resistance, endangering food safety, etc. Effect

Active Publication Date: 2014-04-30
河北普德动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the injection of vaccine antibodies has immune hysteresis, and if ducks and geese are infected, even injections of vaccine antibodies are ineffective; antiviral and antibiotics and other chemical drugs are used for treatment, and drug resistance is prone to occur, and due to the long half-life of such drugs, A large amount of drug residues will be produced in poultry meat and egg products, which will endanger food safety and eventually cause adverse effects on human health

Method used

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  • Pharmaceutical composition for treating duck and goose flavivirus infection and preparation method thereof
  • Pharmaceutical composition for treating duck and goose flavivirus infection and preparation method thereof
  • Pharmaceutical composition for treating duck and goose flavivirus infection and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The preparation of embodiment 1 pharmaceutical composition

[0029] 1) Weigh the component raw materials according to the following weight

[0030] Povidone iodine (containing 10% available iodine) 1.5kg, borneol 8.5kg, Scutellaria baicalensis extract (oral grade 10:1) 15kg, β-cyclodextrin 25kg, glucose 30kg, Jiayi powder 20kg.

[0031] 2) Dissolve borneol with 25kg of absolute ethanol, add it to povidone-iodine, seal and mix for 15 minutes, add the mixed drug solution to β-cyclodextrin coating, heat to recover ethanol; Pulverize and pass through a 100-mesh sieve; mix the Scutellaria baicalensis extract, glucose, Jiayi powder and povidone-iodine-borneol powder, pass through a 100-mesh sieve and pack to obtain the final product.

Embodiment 2

[0032] The preparation of embodiment 2 pharmaceutical compositions

[0033] 1) Weigh the component raw materials according to the following weight

[0034] Povidone iodine (containing 10% available iodine) 0.5kg, borneol 15kg, Scutellaria baicalensis extract (oral grade 10:1) 20kg, β-cyclodextrin 30kg, glucose 25kg, Jiayi powder 9.5kg.

[0035] 2) Dissolve borneol with 45kg of absolute ethanol, add it to povidone-iodine, seal and mix for 10 minutes, add the mixed medicinal solution to β-cyclodextrin coating, heat to recover ethanol; Pulverize and pass through a 200-mesh sieve; mix the Scutellaria baicalensis extract, glucose, Jiayi powder and povidone-iodine-borneol powder, pass through a 80-mesh sieve and pack to obtain the final product.

Embodiment 3

[0036] The preparation of embodiment 3 pharmaceutical compositions

[0037] 1) Weigh the component raw materials according to the following weight

[0038] Povidone iodine (containing 10% available iodine) 3kg, borneol 5.5kg, Scutellaria baicalensis extract (oral grade 10:1) 20kg, β-cyclodextrin 22kg, glucose 40kg, Jiayi powder 9.5kg;

[0039] 2) Dissolve borneol with 11kg of absolute ethanol, add it to povidone-iodine, seal and mix for 20 minutes, add the mixed drug solution to β-cyclodextrin coating, heat to recover ethanol; Pulverize and pass through a 80-mesh sieve; mix the Scutellaria baicalensis extract, glucose, Jiayi powder and povidone-iodine-borneol powder, pass through a 200-mesh sieve and pack to obtain the final product.

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Abstract

The invention provides a pharmaceutical composition for treating duck and goose flavivirus infection and a preparation method thereof. The pharmaceutical composition comprises the following raw material components in percentage by weight: 0.5-3% of povidone iodine, 5.5-15% of borneol, 8-20% of a scutellaria baicalensis extract, 20-30% of beta-cyclodextrin, 25-40% of glucose and 9.5-30% of jia-yi powder. The pharmaceutical composition has the characteristics of convenience for use, safety, effectivity and low cost; meanwhile the preparation method of the pharmaceutical composition is simple to operate, and suitable for large-scale production and application.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicines, and relates to a pharmaceutical composition for treating flavivirus infection and a preparation method thereof, in particular to a pharmaceutical composition for treating duck and goose yellow virus infection and a preparation method thereof. Background technique [0002] Duck and goose yellow virus infection is a common disease mainly characterized by encephalitis-like symptoms, heart, liver, fallopian tube, and ovarian hemorrhage, atrophic fatty lesions, and the main clinical manifestations of ducks and geese are unsteady standing, feed intake Rapid decline, sudden drop in egg production, and increased mortality. In the breeding of ducks and geese, the incidence of flavivirus infection is high, the course of the disease is long, and the mortality rate is high, and the incidence rate is increasing year by year, which has caused serious economic losses to the breeding industry. [0...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K47/48A61P31/14A61K31/79A61K31/045
Inventor 刘明潘晓红王慧彬郭永红
Owner 河北普德动物药业有限公司
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