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Whitening traditional Chinese medicine composition as well as preparation method and application thereof

A composition and whitening technology, applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve problems such as hidden dangers, poor effect of whitening products, etc., and achieve the effect of inhibiting activity

Active Publication Date: 2014-05-28
TIANJIN JIASHITANG SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most of the whitening products on the market are not effective, and some products bring some hidden dangers while whitening the skin. Therefore, there is a need for a whitening product that is safe, effective, and stable in efficacy

Method used

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  • Whitening traditional Chinese medicine composition as well as preparation method and application thereof
  • Whitening traditional Chinese medicine composition as well as preparation method and application thereof
  • Whitening traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A preparation method of a traditional Chinese medicine whitening composition, comprising the steps of:

[0025] (1) Weigh the following raw materials in parts by weight: 30 parts of safflower, 30 parts of Panax notoginseng, 20 parts of dried blood, 20 parts of persimmon leaves;

[0026] (2) Take safflower, crush it, use 75% ethanol aqueous solution with a volume fraction 8 times the weight of safflower, heat and reflux to extract twice, each time for 3 hours, filter the extract, and concentrate the filtrate under reduced pressure to a density of 1.5g / mL of thick paste;

[0027] (3) Take Panax notoginseng, crush it, heat and reflux extraction twice with ethyl acetate that is 8 times the weight of Panax notoginseng, each time for 3 hours, filter the extract, and concentrate the filtrate under reduced pressure to a thick paste with a density of 1.5g / mL;

[0028] (4) Take dried blood, pulverize it, heat and reflux the aqueous solution of ethanol with a volume fraction of ...

Embodiment 2

[0032] A preparation method of a traditional Chinese medicine whitening composition, comprising the steps of:

[0033] (1) Weigh the following raw materials in parts by weight: 25 parts of safflower, 35 parts of Panax notoginseng, 15 parts of dried blood, and 25 parts of persimmon leaves;

[0034] (2) Take safflower, crush it, use 10 times the weight of safflower with 50% ethanol aqueous solution, heat and reflux to extract once, 4 hours each time, filter the extract, and concentrate the filtrate under reduced pressure to a density of 1g / mL thick paste;

[0035] (3) Take Panax notoginseng, crush it, heat and reflux extraction once with chloroform of 10 times the weight of Panax notoginseng, each time for 4 hours, filter the extract, and concentrate the filtrate under reduced pressure to a thick paste with a density of 1g / mL;

[0036] (4) Take dried blood, pulverize it, heat and reflux extract once with 95% ethanol aqueous solution, 10 times the weight of dried dried blood, fo...

Embodiment 3

[0040] A preparation method of a traditional Chinese medicine whitening composition, comprising the steps of:

[0041] (1) Weigh the following raw materials in parts by weight: 35 parts of safflower, 25 parts of Panax notoginseng, 25 parts of dried blood, and 15 parts of persimmon leaves;

[0042] (2) Take safflower, crush it, use 6 times the weight of safflower in an aqueous ethanol solution with a volume fraction of 95%, heat and reflux to extract 3 times, each time for 2 hours, filter the extract, and concentrate the filtrate under reduced pressure to a density of 2g / mL thick paste;

[0043] (3) Take Panax notoginseng, crush it, heat and reflux extract 3 times with petroleum ether 6 times the weight of Panax notoginseng, each time for 2 hours, filter the extract, and concentrate the filtrate under reduced pressure to a thick paste with a density of 2g / mL;

[0044] (4) Take dried blood, pulverize it, heat and reflux extract with 95% ethanol aqueous solution which is 6 times...

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Abstract

The invention discloses a whitening traditional Chinese medicine composition as well as a preparation method and application thereof. The preparation method comprises the steps as follows: raw materials comprising safflower, notoginseng, sanguis draconis and persimmon leaf are weighed; the safflower is taken, crushed and then subjected to heating, reflux extraction is performed through an alcohol aqueous solution, and an extraction solution is filtered, and pressure-reduction concentration is performed to obtain a thick paste; the notoginseng is taken and crushed, heating reflux extraction is performed through petroleum ether, chloroform or acetidin, and an extraction solution is filtrated, and pressure-reduction concentration is performed to obtain another thick paste; the sanguis draconis is taken and crushed, pressure-reduction concentration is performed through a 95-percent alcohol aqueous solution, an extraction solution is filtrated, pressure-reduction concentration is performed through to remove alcohol, so that a concentrated solution is obtained, the concentrated solution is placed in water, uniformly agitated, filtrated, extracted by the petroleum ether and then extracted through acetidin to obtain a third thick paste; the persimmon leaf is taken, and crushed, heating reflux extraction is performed through the alcohol aqueous solution, an extraction solution is filtered, and pressure-reduction concentration is performed to obtain a fourth thick paste; all the thick pastes are uniformly mixed. Experiment results show that the whitening traditional Chinese medicine composition disclosed by the invention can resist the activity of tyrosinase, and enables the skin to keep healthy and white for a long time.

Description

technical field [0001] The invention relates to a traditional Chinese medicine whitening composition, a preparation method and application thereof. Background technique [0002] Because of the traditional concept of "one white covers one hundred ugliness", Asian women regard whiteness as beauty; in Western countries, due to a series of skin problems caused by sun exposure in recent years, whitening has also become a trend, so the demand for whitening products increasing day by day. [0003] At present, most of the whitening products on the market are not effective, and some products bring some hidden dangers while whitening the skin. Therefore, there is a need for a safe, effective and stable whitening product. [0004] The color of human skin is mainly determined by the content and concentration of melanin in the skin. Tyrosinase is a key enzyme involved in the synthesis of melanin in organisms. It is a copper-containing multi-subunit oxidoreductase widely present in natur...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02
Inventor 丁利营雷虔朱永琴李红艳
Owner TIANJIN JIASHITANG SCI & TECH
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