A kind of preparation method of spirulina polysaccharide
A technology of spirulina polysaccharide and spirulina, which is applied in the field of preparation of spirulina polysaccharide, can solve the problems of large consumption of organic solvents, low sugar extraction rate, long process flow, etc., avoid the use of organic solvents, improve the purity, simple craftsmanship
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Embodiment 1
[0018] Take 100g of spirulina algae powder, use pH=8.0 NaOH aqueous solution as the extraction solution, stir and extract for 2 hours (90°C water bath, solid-to-liquid ratio 1:15), centrifuge to take the supernatant, adjust the pH value to 4.0, and centrifuge again to take the supernatant The liquid is the upper column liquid. Flow through a cation exchange resin column 732 (10×100 cm) at a flow rate of 1 bed volume / hour to collect polysaccharide components, use a 10kDa ultrafiltration membrane for concentration and desalination, and then spray dry to obtain high-purity polysaccharide powder. The product is pale yellow with a purity of 96.3%.
Embodiment 2
[0020] Take 10 g of low-purity spirulina polysaccharide (purity 30.2%), use water as the extraction solution, stir and dissolve for 10 min (60°C water bath, solid-to-liquid ratio 1:30), adjust the pH value to 4.0, and centrifuge to remove the precipitate. Adjust the pH to 10, and centrifuge again to get the supernatant, which is the upper column liquid. Flow through anion exchange resin D254 (20×100cm) at a flow rate of 1 bed volume / hour, and use 2% sodium chloride solution for dynamic elution. It is the upper column liquid. The polysaccharide fraction was collected, concentrated and desalted using a 10kDa ultrafiltration membrane, and then freeze-dried to obtain a high-purity polysaccharide powder. The product is white with a purity of 98.5%.
Embodiment 3
[0022] Take 100g of fresh spirulina, use pH=9.0NaOH aqueous solution as the extraction solution, stir and extract for 2h (100℃ water bath, solid-to-liquid ratio 1:10), centrifuge to get the supernatant, adjust the pH value to 3.0, centrifuge again to get the supernatant The liquid is the upper column liquid. Flow through a cation exchange resin column D113 (10×100 cm) at a flow rate of 1 bed volume / hour to collect polysaccharide fractions, use a 10kDa ultrafiltration membrane for concentration and desalination, and then freeze-dry to obtain high-purity polysaccharide powder. The product is white with a purity of 97.1%.
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