Traditional Chinese medicinal composition for treating irritable bowel syndrome and preparation method of composition

The technology of a composition and traditional Chinese medicine, applied in the field of preparation of the composition, can solve the problems of lack of drugs, no treatment plan, reduced effective rate and the like, and achieve the effect of good curative effect

Active Publication Date: 2014-06-11
SHIJIAZHUANG YILING PHARMA
View PDF1 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the in-depth research on enteric nervous system mediators and their receptors, 5-HT receptor modulators can not only regulate colon motility response but also reduce visceral hypersensitivity, but they can also cause severe constipation and dyspepsia in patients with diarrhea-type IBS. Clinical use is limited due to bloody enteritis
In addition, the therapeutic effect of drugs on IBS-D will decrease over time, and the disease is prone to relapse. For example, trimebutine maleate can significantly improve the symptoms of abdominal pain and diarrhea in patients with diarrhea-type IBS. The total effective rates at one month were 79.5% and 51.4%, respectively. The short-term ...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 Preparation of Chang'an No. 1 Prescription of Chinese Medicine Composition for the Treatment of Irritable Bowel Syndrome

[0021] 1) Weigh 500 grams of astragalus, 500 grams of fried Atractylodes macrocephala, 650 grams of fried white peony root, 250 grams of Fangfeng, 160 grams of Coptis chinensis, 160 grams of paojiang charcoal, 250 grams of nutmeg, 250 grams of Qing Pinellia, 320 grams of simmering wood fragrance, 160 grams of roasted licorice, 250 grams of tangerine peel;

[0022] 2) Extract Astragalus and Coptidis with 8 times the amount of 70% ethanol for 3 times, each time for 2 hours; combine the ethanol extracts, recover ethanol, concentrate properly, and dry; nutmeg, simmering wood and tangerine peel are properly crushed, and added 10 times Measure water, extract volatile oil with steam distillation, extraction time is 8 hours. Collect the volatile oil, wrap it with cyclodextrin, refrigerate overnight, dry at low temperature, and use the mother liqu...

Embodiment 2

[0023] Embodiment 2: the preparation of decoction

[0024] 1) Weigh 90 grams of astragalus, 90 grams of fried Atractylodes macrocephala, 120 grams of fried white peony root, 45 grams of Fangfeng, 30 grams of Coptis chinensis, 30 grams of paojiang charcoal, 45 grams of nutmeg, 45 grams of Qing Pinellia, 60 grams of simmering wood fragrance, 30 grams of roasted licorice, 45 grams of tangerine peel;

[0025] 2) Add water to decoct the medicinal material for 2-3 times, combine the medicinal liquid, filter and concentrate to obtain a decoction.

Embodiment 3

[0026] Embodiment 3: the preparation of capsule

[0027] 1) Weigh 250 grams of astragalus, 250 grams of fried Atractylodes macrocephala, 320 grams of fried white peony root, 120 grams of Fangfeng, 80 grams of Coptis chinensis, 80 grams of paojiang charcoal, 120 grams of nutmeg, 120 grams of Qing Pinellia, 160 grams of simmering wood fragrance, 80 grams of roasted licorice, 120 grams of tangerine peel;

[0028] 2) Extract Astragalus and Coptidis with 8 times the amount of 70% ethanol for 3 times, each time for 2 hours; combine the ethanol extracts, recover ethanol, concentrate properly, and dry; nutmeg, simmering wood and tangerine peel are properly crushed, and added 10 times Measure water, extract volatile oil with steam distillation, extraction time is 8 hours. Collect the volatile oil, wrap it with cyclodextrin, refrigerate overnight, dry at low temperature, and use the mother liquor for later use; extract Atractylodes macrocephala, fried white peony root, Paojiang charcoa...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a traditional Chinese medicinal composition for treating liver depression and spleen deficiency type irritable bowel syndrome. The composition is an active component prepared from the following traditional Chinese medicinal materials: astragalus membranaceus, fried bighead atractylodes rhizome, fried white peony root, divaricate saposhnikovia root, coptis chinensis, blast-fried ginger, myristica fragrans, rhizoma pinelliae preparata, baked costustoot, roasted liqourice and dried tangerine peel, and can be prepared into various oral preparation forms by addition of pharmaceutically common auxiliaries. Clinical application indicates that the traditional Chinese medicinal composition is remarkable in curative effect for improving the symptom. The invention also discloses a preparation method of the composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating irritable bowel syndrome of liver stagnation and spleen deficiency type, and also relates to a preparation method of the composition. Background technique [0002] Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder with a high incidence worldwide, and its main symptoms are abdominal pain or discomfort accompanied by changes in bowel habits. IBS is one of the most common functional gastrointestinal diseases clinically. Although it is not life-threatening, it can affect work and life to varying degrees, occupy a large amount of medical resources, and cause a serious decline in quality of life. In recent years, it has become a research topic at home and abroad. hotspot. [0003] At present, there are many drugs for the treatment of IBS clinically, which can be roughly classified into the following four categories: drugs that regulate intestinal motility...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/9068A61P1/00A61K33/12A61K35/56A61K35/618
Inventor 唐旭东
Owner SHIJIAZHUANG YILING PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap