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Traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the directions of drug combination, pharmaceutical formula, boron compound active ingredient, etc., can solve the problems of increased and enlarged nasal polyps, easy bleeding, etc., and achieve the effects of no toxic and side effects, enhanced pharmacological action, and definite curative effect.

Inactive Publication Date: 2014-08-06
SHENZHEN RUILAI GUISHENG BIOMEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0025] 4. Hemorrhagic polyps (rare) have smooth surface, congested, soft to the touch and easy to bleed
[0028] 7. Nasal polyps increase and become larger. If left untreated for a long time, the back of the nose can widen and form a "frog nose"

Method used

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  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Weigh 10 grams of honeysuckle, 15 grams of forsythia, and 20 grams of Scutellaria baicalensis as raw materials. A total of 45 grams of the above three medicines, soaked in warm water for 30 minutes, decocted twice for 0.5 hours each time, filtered, combined the filtrates, concentrated to a relative density of 1.20-1.25 (70-80°C), let cool to 40°C , slowly add ethanol to make the alcohol content reach 75%, stir well, let it stand for 12 hours, filter the supernatant, recover the ethanol until it tastes alcohol, add 3 to 4 times the amount of water, let it stand for 12 hours, filter the supernatant Concentrate to a relative density of 1.10-1.50 (70-80°C), let it cool to 40°C, add ethanol to make the alcohol content reach 85%, let it stand for more than 12 hours, filter the supernatant, and put it into a vacuum concentration tank Or the alcohol recovery tower reclaims ethanol until the liquid has no alcohol smell, and it is set aside. Dilute the liquid with 1000ml of dist...

Embodiment 2

[0050] Weigh 10 grams of honeysuckle, 15 grams of forsythia, and 20 grams of Scutellaria baicalensis as raw materials. A total of 45 grams of the above three medicines, soaked in warm water for 30 minutes, decocted twice for 0.5 hours each time, filtered, combined the filtrates, concentrated to a relative density of 1.20-1.25 (70-80°C), let cool to 40°C , slowly add ethanol to make the alcohol content reach 75%, stir well, let it stand for 12 hours, filter the supernatant, recover the ethanol until it tastes alcohol, add 3 to 4 times the amount of water, let it stand for 12 hours, filter the supernatant Concentrate to a relative density of 1.10-1.50 (70-80°C), let it cool to 40°C, add ethanol to make the alcohol content reach 85%, let it stand for more than 12 hours, filter the supernatant, and put it into a vacuum concentration tank Or the alcohol recovery tower reclaims ethanol until the liquid has no alcohol smell, and it is set aside. Dilute the liquid with 1000ml of dist...

Embodiment 3

[0052] Weigh 10 grams of honeysuckle, 15 grams of forsythia, and 20 grams of Scutellaria baicalensis as raw materials. A total of 45 grams of the above three medicines, soaked in warm water for 30 minutes, decocted twice for 0.5 hours each time, filtered, combined the filtrates, concentrated to a relative density of 1.20-1.25 (70-80°C), let cool to 40°C , slowly add ethanol to make the alcohol content reach 75%, stir well, let it stand for 12 hours, filter the supernatant, recover the ethanol until it tastes alcohol, add 3 to 4 times the amount of water, let it stand for 12 hours, filter the supernatant Concentrate to a relative density of 1.10-1.50 (70-80°C), let it cool to 40°C, add ethanol to make the alcohol content reach 85%, let it stand for more than 12 hours, filter the supernatant, and put it into a vacuum concentration tank Or the alcohol recovery tower reclaims ethanol until the liquid has no alcohol smell, and it is set aside. Dilute the liquid with 1000ml of dist...

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Abstract

The invention discloses traditional Chinese medicine composition as well as an application thereof to preparation of drugs and hygienic products for treating adenoidal hypertrophy and nasal polyp. The traditional Chinese medicine composition comprises active pharmaceutical ingredients by weight as follows: 5-25 g of honeysuckle flowers, 5-25 g of fructusforsythiae and 5-25 g of baical skullcap roots. The traditional Chinese medicine composition is prepared from the honeysuckle flowers, the fructusforsythiae and the baical skullcap roots by weight, has effects of clearing heat and toxic materials, relieving sore throat and relieving swelling, and can be mixed with pharmaceutically allowableintravenous drip liquids and excipients to be prepared into preparations acceptable for patients. Orthogonal tests confirm that the honeysuckle flowers are 10 g, the fructusforsythiae is 15 g and the baical skullcap roots are 20 g by weight, the decoction time is 30 min, and the antibacterial curative effect of the traditional Chinese medicine composition is best when the PH is 7.5; in-vitro experiments prove that the traditional Chinese medicine composition has good antibacterial and anti-inflammation effects; nasal root instillation or nasal cavity flushing or nasal root smearing clinically proves that the traditional Chinese medicine composition has significant effects on treating the adenoidal hypertrophy and the nasal polyp and is good in safety.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating adenoid hypertrophy and nasal polyps and a preparation method thereof. It involves mixing the powder prepared by the traditional Chinese medicine honeysuckle, forsythia, and scutellaria baicalensis with pharmaceutically permitted intravenous infusion liquids and excipients to make preparations acceptable to patients, including nasal liquid preparations and nasal semi-solid preparations. Local administration for the treatment of adenoid hypertrophy and nasal polyps. Background technique [0002] 1. Adenoid hypertrophy [0003] Adenoids, also known as pharyngeal tonsils and proliferating bodies, are located on the roof and back wall of the nasopharynx. They are part of the pharyngeal lymphatic ring and belong to the immune organs of the human body. They contain lymphocytes at various stages of developmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61P11/02A61K35/56A61K35/413A61K35/32A61K35/10A61K33/30A61K33/22A61K33/20A61K31/045A61K33/28A61K31/125A61K33/04
Inventor 曲敬来高雪陈生齐继贵
Owner SHENZHEN RUILAI GUISHENG BIOMEDICAL TECH CO LTD
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