Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Vaccine Composition

A vaccine composition and composition technology, applied in the direction of drug combination, heterocyclic compound active ingredients, drug delivery, etc., can solve the problems of low cancer occurrence rate, difficult to administer to patients with needle stick infection accidents, and unclear mechanism of action, etc. Achieve the effect of high-efficiency cellular immunity induction effect

Inactive Publication Date: 2014-08-06
NITTO DENKO CORP
View PDF16 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, injections have the following problems: pain, fear, injection scars and scars developed from injection scars, only medical workers can perform injections, intradermal injections with high immune effects are difficult to administer, and there are needles for medical workers. It cannot be said to be the best route of administration because of the risk of infection accidents, the need to go to the hospital frequently when repeated administration is a burden on the patient's life, and the generation of medical waste that requires special disposal such as injection needles.
In addition, if it is limited to the induction of cellular immunity, for injection, Freund's adjuvant, Montanide, GM-CSF, IL-2, IL-12, and IFN-γ have been studied, but they have not been practical yet. For transdermal administration , mucosal administration, only toxins such as cholera toxin and Escherichia coli heat-labile toxin, and nucleic acids have very few reports
[0006] In addition, anti-inflammatory drugs such as loxoprofen and aspirin have reported a low incidence of cancer in patients taking them through large-scale epidemiological investigations (Non-Patent Documents 3 to 5), but their mechanism of action is unclear. Unclear, it is believed that one of the causes is the inhibition of the production of PGE2 released when cancer cells metastasize

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Vaccine Composition
  • Vaccine Composition
  • Vaccine Composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0420] materials used

[0421] Imiquimod: manufactured by Tokyo Kasei Kogyo, clofibrate: manufactured by LKT Laboratories, fenofibrate: manufactured by Wako Pure Chemical Industries, quercetin: manufactured by Cayman Chemical, berberine (berberine hydrochloride n-hydrate): Manufactured by Wako Pure Chemical Industries, Nascotin: Manufactured by Wako Pure Chemical Industries, 3,3'-diindolylmethane: Manufactured by Wako Pure Chemical Industries, xanthonone: Manufactured by Wako Pure Chemical Industries, parthenolide: Manufactured by Wako Pure Chemical Industries, Etodo Acid: Manufactured by Wako Pure Chemical Industries, Loxoprofen (Loxoprofen Na): Manufactured by Yoshindo, Indomethacin: Manufactured by Wako Pure Chemical Industries, Aspirin: Manufactured by Sigma-Aldrich, Diclofenac (Diclofenac Sodium): Manufactured by Wako Pure Chemical Industries Production, Ketoprofen: Manufactured by Wako Pure Chemical Industries, Celecoxib: Manufactured by TOCRIS Bioscience, Valdecoxib: ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction promoter.

Description

technical field [0001] The invention relates to a vaccine composition for inducing cellular immunity. Background technique [0002] Vaccines that are generally and widely used are substances administered to pathogens such as microorganisms or viruses or parts thereof for the purpose of inducing immunity. In addition, there are cancer vaccines aimed at enabling the cellular immune system to recognize cancer cell-specific antigens and inducing the immune system to specifically attack cancer cells. This vaccine is used as one of the means of cancer treatment. [0003] Usually, microbes, viruses can be prevented from entering through the skin due to their size, therefore, vaccines need to be administered invasively into the body. Thus, immunization usually uses injections. However, injections have the following problems: pain, fear, injection scars and scars developed from injection scars, only medical workers can perform injections, intradermal injections with high immune eff...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/39A61K39/00A61K9/00A61P37/04A61P35/00A61P31/00
CPCA61K31/192A61K31/196A61K31/216A61K31/353A61K31/4035A61K31/405A61K31/407A61K31/415A61K31/42A61K31/426A61K31/5575A61K31/616A61K38/10A61K39/0011A61K2039/54A61K2039/572A61P31/00A61P35/00A61P37/00A61P37/04A61K38/08A61K39/00A61K45/06A61K2039/541A61K9/0014A61K39/39
Inventor 浅利大介大久保胜之宍户卓矢冈崎有道前田佳己松下恭平李文婧堀光彦杉山治夫
Owner NITTO DENKO CORP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com