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A kind of uterine epithelial cell variation and cervical erosion model drug for external use

A technology of epithelial cells and cervical erosion, which is applied in the direction of medical formula, drug combination, drug delivery, etc., can solve the problems of poor controllability of the treatment process, ambiguous administration of drug administration, and poor drug pertinence, so as to facilitate the treatment cycle , lightening treatment, highly targeted effect

Active Publication Date: 2016-08-24
陈则均
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Common treatment methods for cervical erosion and cervical cancer are mainly divided into three types: surgical method, drug method and molecular genetic method. The surgical method is less used because it is prone to scarring and large trauma; the drug method mainly uses oral antibiotics. 1. Vaginal medication such as gynecological suppositories or lotions, etc., but this method has a long treatment cycle, ambiguous administration, poor drug pertinence, slow curative effect, and poor controllability of the treatment process; although the molecular gene method Can play a certain targeting role, but the treatment process is long, the cost is high, and the universality is not good

Method used

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  • A kind of uterine epithelial cell variation and cervical erosion model drug for external use

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Experimental program
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Embodiment 1

[0021] In this embodiment, a kind of uterine epithelial cell variation, cervical erosion model drug for external use, combined with figure 1 , including the opening 1, the main body 2 and the bottom 3, the inner diameter of the opening 1 is larger than the outer diameter of the bottom 3, the main body 2 is located between the opening 1 and the bottom 3, the main body 2 and the bottom 3 are integrated structure, the opening 1, the main body 2 and the bottom 3 A trumpet-shaped structure is formed, wherein the ingredients of the main body 2 and the bottom 3 are: 3 grams of forsythia, 10 grams of Brucea javanica, 10 grams of Patrinia, 10 grams of wild peony; Peony is in the form of extract, and the rest are in the form of nano-scale (or about 300 mesh) powder. The above-mentioned main drug and auxiliary drug are supplemented with medicinal gelatin (10-35g, depending on the model, the amount of medicinal gelatin can vary. Choose 35g, 20g and 10g to form No. 1 drug, No. 2 drug, and ...

Embodiment 2

[0024] In this embodiment, the ingredients of the main body 2 and the bottom 3 are: 6 grams of Brucea javanica, 3 grams of Coptis chinensis, 6 grams of comfrey, and 7 grams of wild peony; among the ingredients of the above-mentioned main medicine and auxiliary medicine, comfrey is in the form of extracted oil, Wild peony is in the form of extract, and the rest are nano-scale (or about 300 mesh) powder. The above-mentioned main drug and auxiliary drug are supplemented with medicinal gelatin (10-35g, depending on the model, the amount of medicinal gelatin input 35g, 20g and 10g can be selected to form No. 1 drug, No. 2 drug and No. 3 drug respectively) to make a model simulating the structure of the cervix for targeted drug delivery; among them, Brucea javanica acts as the main drug to corrode warts , so that the ectopic cervical columnar epithelium falls off, and the cervical squamous epithelium that should have appeared in the corresponding position appears, so as to achieve th...

Embodiment 3

[0027] In this embodiment, the ingredients of the main body 2 and the bottom 3 are: 2 grams of borneol, 3 grams of Brucea javanica, 15 grams of Patrinia, 6 grams of Forsythia, 5 grams of Coptis chinensis, and 5 grams of Curcuma; The ingredients are all nano-scale (or about 300 mesh) powder, and the above-mentioned main drug and auxiliary drug are supplemented with medicinal gelatin (10-35g, depending on the model, the input amount of medicinal gelatin can be selected as 35g, 20g and 10g, forming No. 1 drug, No. 2 drug, and No. 3 drug respectively) to make a model simulating the structure of the cervix for targeted drug administration; among them, Brucea javanica as the main drug has the effect of corroding warts, making the ectopic cervical columnar The epithelium falls off, and the squamous epithelium of the cervix that should have appeared in the corresponding position is revealed, thereby achieving the effect of eliminating cervical columnar epithelium and cervical erosion; ...

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Abstract

The invention relates to an external-applied model drug for treating cervical cancer and cervical erosion, which belongs to the technical field of biological agent. The model drug performs targeted drug delivery by simulating a model of a cervical structure, the model drug is in a barrel structure composed of an opening, a main body and a bottom, opening diameter is larger than bottom diameter, the components of the main body and the bottom are same and comprise a main drug and an auxiliary drug, the main drug is brucea javanica, the auxiliary drug is a mixture of fructus forsythia, patrinia herb and wild peony. The external-applied model drug used for the patients with cervical cancer and cervical erosion, and has the advantages of strong targeting, good controllability and high treatment efficiency.

Description

technical field [0001] The invention relates to an externally used model drug for uterine epithelial cell variation and cervical erosion, belonging to the technical field of biological preparations. Background technique [0002] Cervical erosion, namely cervical columnar epithelium, is due to acute and chronic cervicitis that has not been effectively treated, cervical squamous epithelium falls off, and is replaced by columnar epithelium of the cervical canal, which is manifested as cervical erosion. Clinically, according to the size of the cervical erosion area, Cervical erosion is divided into Ⅰ, Ⅱ, Ⅲ degrees. Cervical erosion will not only affect the life and work of patients, but also has many complications, especially closely related to the incidence of cervical cancer, and cervical cancer is one of the most common cancers in the human body. Cancer occupies the first place, and it is the most common cancer among various malignant tumors in women. [0003] Common treatm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/634A61K36/9066A61K36/902A61K9/00A61P15/00A61K31/045A61K31/722
Inventor 陈则均
Owner 陈则均
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