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Traditional Chinese medicine for treating bacterial vaginosis and preparation method of traditional Chinese medicine

A vaginitis and bacterial technology, applied in the field of medical preparations, can solve problems such as inability to adhere to treatment, unacceptable to patients, large gastrointestinal reactions, etc., and achieve the effect of not easy to relapse, less toxic and side effects, and exact curative effect

Inactive Publication Date: 2014-09-03
陈维燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The most effective treatment is the first choice of oral metronidazole, but due to the large gastrointestinal reactions of oral metronidazole, patients should not accept or cannot adhere to the treatment. In recent years, they tend to use vaginal topical drugs. The effect can also reduce side effects, but there are still some side effects

Method used

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Examples

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Effect test

preparation example Construction

[0042] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is suppository, and its preparation method comprises the following steps:

[0043] The first step: add 4 to 6 times the amount of water to the raw materials and soak for 30 minutes to 1 hour, heat and boil for 50 to 60 minutes, filter, and use the filtrate for later use; add 3 to 5 times the amount of water to the filter residue and heat for the second time, and boil for 40 to 50 minutes, filter, and the filtrate is set aside; add 2 to 4 times the amount of water to the filter residue, heat and boil for the third time for 30 to 40 minutes, and filter; combine the three filtrates together, heat and concentrate to a paste, and dry in an oven at 80°C After cooling, grind into fine powder;

[0044] Step 2: Take one or more of semi-synthetic fatty acid glycerides, lanolin, polyethylene glycol, and poloxamer as a matrix; heat and me...

Embodiment 1

[0051] Embodiment 1 suppository

[0052] Take 70g of motherwort, 60g of purslane, 160g of lettuce, 220g of Jinjinxiang, 240g of small flying canopy, 80g of flying grass, 60g of hanging bamboo plum, 140g of wild amaranth, 440g of chaotian can, 70g of phoenix crown grass, 330g of yellow vine, and white fresh 180g skin, 160g five-color plum, 120g duck celery, 130g Yisaoguang and 140g red back leaf;

[0053] Prepare as follows:

[0054] The first step: soak the above raw materials with 5 times the amount of water for 1 hour, heat and boil for 60 minutes, filter, and the filtrate is set aside; add 4 times the amount of water to the filter residue and heat for the second time, boil for 50 minutes, filter, and the filtrate is set aside; Double the amount of water, heat for the third time and boil for 40 minutes, filter; combine the three filtrates, heat and concentrate to a paste, put it in an oven at 80°C, dry it, cool it, and grind it into a fine powder;

[0055] The second step:...

Embodiment 2

[0056] Embodiment 2 lotion

[0057] Take 80g of motherwort, 70g of purslane, 180g of lettuce, 240g of Jinjinxiang, 220g of small flying canopy, 60g of flying grass, 70g of hanging bamboo plum, 110g of wild amaranth, 410g of chaotian can, 80g of phoenix crown grass, 320g of yellow rattan, white fresh 160g skin, 180g five-color plum, 140g duck celery, 110g Yisaoguang and 110g red back leaf;

[0058] Prepare as follows:

[0059] The first step: mix the above-mentioned raw materials in proportion, put them into an ultrafine pulverizer and pulverize them into a mixed powder composed of micron-sized particles with a volume average particle size of 1 μm and nano-sized particles with a volume average particle size of less than 0.1 μm, The powder yield of the mixed powder is at least 95%;

[0060] Step 2: Add ethanol with an alcohol concentration of 90% relative to the mass of the mixed powder that is 5 times the mass of the mixed powder to the mixed powder obtained in the first step...

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Abstract

The invention provides a traditional Chinese medicine for treating bacterial vaginosis and a preparation method of the traditional Chinese medicine. Material medicines of the traditional Chinese medicine comprise: polygonum chinense, purslane, endive, Chinese osbeckia herb, horseweed herb, hairy euphorbia, wandering jew, amaranthus viridis, wideleaf osbeckia root, herb of sword brake, herba fibraureae recisae, dictamni cortex, lantana camara, cryptotaenia japonica hassk, senecio dianthus franch and root or leaf of redback christmashush. The traditional Chinese medicine disclosed by the invention is mainly used for clearing away heat and removing dampness, removing pattogenic heat from the blood and toxic material from the blood, sterilizing and relieving itching, has extract curative effect on bacterial vaginitis, is small in toxic and side effect, and does not easily have a relapse.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating bacterial vaginosis and a preparation method thereof. Background technique [0002] Bacterial vaginosis (BV) is one of the common gynecological inflammations. It is a mixed bacterial infection, mainly manifested as increased vaginal discharge and foul odor. May have mild genital itching or burning sensation, easy to relapse, contagious, 10-40% of patients have no clinical symptoms, seriously affecting the quality of life of patients. [0003] BV is characterized by changes in the vaginal environment, that is, the dominant lactobacilli are replaced by a large number of pathogenic anaerobic bacteria, so metronidrone, which is effective against anaerobic bacteria, is usually used for clinical treatment. The most effective treatment is the first choice of oral metronidazole, but due to ...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P15/02A61P31/04A61P31/02
Inventor 张晓燕许梅华薛卫强薛君栾英杰顾维乐孙永国李艳红陈勋魏秀芝张阳
Owner 陈维燕
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