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Decayed-tooth-resistant chewing gum

A chewing gum and dental caries technology, which is applied in antibacterial drugs, drug delivery, plant raw materials, etc., can solve the problems of teeth yellowing, limited curative effect, and taste change, and achieve the effect of less irritation, mild nature, and strong binding ability

Active Publication Date: 2014-10-15
GUILIN SHILI SCI & TECH COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the anti-caries products used in the market are roughly divided into the following categories: one is fluorine-containing preparations, and its anti-caries raw materials are to promote tooth calcification and reduce acid corrosion, which is an indirect effect and has limited efficacy; the other is the application of antibacterial drugs, such as Cortex and iodophor, the main components of Cortex are chlorhexidine, metronidazole, glycerin and other substances. Cortac can be adsorbed on the surface of tooth enamel, oral mucosa and plaque, and released slowly, with a fairly strong broad-spectrum Antibacterial and bactericidal effects, and can prevent the occurrence of oral infections, but long-term use can cause side effects such as yellowing of teeth and changes in taste

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 1) Ingredients: Luo Han Guo 8kg, Licorice 1kg, Galla chinensis 1kg, Angelica dahurica 1kg, Mint 0.5kg, Clove 0.5kg, Lotus leaf 1kg.

[0016] 2) Put mint and clove in ethanol, reflux extraction at 80°C for 0.5h, centrifuge the extract, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.10 at 60°C;

[0017] 3) Crush the rest of the raw materials, soak them in water, decoct at 85°C for 1 hour, filter the decoction, add ethanol to the filtrate for precipitation, filter out the precipitate, and concentrate under reduced pressure to an extract with a relative density of 1.05 at 60°C;

[0018] 4) mixing the extracts of step 2) and step 3), which is the traditional Chinese medicine composition;

[0019] 5) Mix 0.2kg of traditional Chinese medicine composition and 99.8kg of gum base, heat at 50-60°C until it melts, stir well, and cool to form candy base; roll sugar base into sugar tablets, cool, and cut into pieces to obtain ....

Embodiment 2

[0021] 1) Ingredients: Luo Han Guo 15kg, Licorice 5kg, Galla chinensis 3kg, Angelica dahurica 2kg, Mint 1.5kg, Clove 1kg, Lotus leaf 3kg.

[0022] 2) Put mint and cloves in ethanol, reflux extraction at 85°C for 3 times, each extraction for 1.5h, combine the extracts, centrifuge, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.25 at 60°C;

[0023] 3) Grind the rest of the raw materials, soak them in water, decoct 3 times at 95°C for 2 hours each time, combine the decoction liquid, filter, add ethanol to the filtrate for precipitation, filter off the precipitate, and concentrate under reduced pressure to 60°C. An extract with a density of 1.15;

[0024] 4) mixing the extracts of step 2) and step 3), which is the traditional Chinese medicine composition;

[0025] 5) Mix 2kg of the traditional Chinese medicine composition and 98kg of gum base, heat at 60°C until it melts, stir well, and cool to form candy base; roll the suga...

Embodiment 3

[0027] 1) Ingredients: Luo Han Guo 8kg, licorice 5kg, Galla chinensis 1kg, Angelica dahurica 2kg, mint 0.5kg, clove 1kg, lotus leaf 1kg, Magnolia officinalis 3kg.

[0028] 2) Put mint and cloves in ethanol, reflux extraction at 80°C for 3 times, each extraction for 0.5h, combine the extracts, centrifuge, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.25 at 60°C;

[0029] 3) Crush the remaining raw materials, add water to soak, decoct at 85°C for 3 times, each time for 1 hour, combine the decoction liquid, filter, add ethanol to the filtrate for precipitation, filter out the precipitate, and concentrate under reduced pressure to 60°C. An extract with a density of 1.15;

[0030] 4) mixing the extracts of step 2) and step 3), which is the traditional Chinese medicine composition;

[0031] 5) Mix 0.2 kg of the traditional Chinese medicine composition with the gum base, heat at 60°C until it melts, stir well, and cool to form...

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PUM

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Abstract

The invention provides a decayed-tooth-resistant chewing gum, which comprises a gum base and a traditional Chinese medicine composition, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8-15 parts of siraitia grosvenorii, 1-5 parts of radix glycyrrhizae, 1-3 parts of gallnut, 1-2 parts of radix angelicae dahuricae, 0.5-1.5 parts of mint, 0.5-1 part of clove, 1-3 parts of lotus leaf and 1-3 parts of cortex magnoliae officinalis. According to the invention, the combining capacity of active ingredients in the decayed-tooth-resistant chewing gum and streptococcus mutans is higher, and the active ingredients can directly enter the streptococcus mutans cells to play the effect of killing bacteria.

Description

technical field [0001] The invention relates to a chewing gum, in particular to an anti-caries chewing gum. Background technique [0002] Dental caries mainly refers to the glycolysis of sugary foods under the action of Streptococcus mutans, the acid produced acts on the teeth, causing the destruction of enamel and dentin. At present, the anti-caries products used in the market are roughly divided into the following categories: one is fluorine-containing preparations, and its anti-caries raw materials are to promote tooth calcification and reduce acid corrosion, which is an indirect effect and has limited efficacy; the other is the application of antibacterial drugs, such as Cortex and iodophor, the main components of Cortex are chlorhexidine, metronidazole, glycerin and other substances. Cortac can be adsorbed on the surface of tooth enamel, oral mucosa and plaque, and released slowly, with a fairly strong broad-spectrum It has antibacterial and bactericidal effects, and c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61K9/68A61P1/02A61P31/04A61K35/64
Inventor 何伟平
Owner GUILIN SHILI SCI & TECH COMPANY
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