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Medical hemostatic sponge material and preparation method thereof

A technology of hemostatic sponge and colloidal materials, applied in medical science, bandages, absorbent pads, etc., can solve the problems of low liquid absorption rate and inability to absorb a large amount of liquid, and achieve the effect of improving porosity and liquid absorption rate

Active Publication Date: 2015-02-18
美迪科(上海)包装材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technical effect that this invented product has added certain chemicals called triglycerolmonostorstal (TG) or tris(hydroxypyran-4)-stabilized starch phospongamic acid (triglycidylethermal gelatin). These ingredients help improve blood clotting by making it easier than traditional methods like fibrin glue. They also enhance the stability of these products during storage over time without losing their ability to absorb liquids quickly enough.

Problems solved by technology

This patented technical problem addressed in this text relates to improving the properties of medical sponging products that provide effective blood clotting while being resistant to inflammation caused by bacterial growth.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] (1) Take an appropriate amount of water, set the water temperature to 60°C, take 8g of xanthan gum, 11g of polyethylene glycol 400, 3g of fibroin, and 19g of polyvinylpyrrolidone by weight, mix the above xanthan gum, Polyethylene glycol 400, fibroin and polyvinylpyrrolidone are dissolved in water and stirred at a stirring speed of 100 rpm for 30 minutes; (2) Add 5 g of triglycerol monostearate, Hydroxypropyl Distarch Phosphate 5g, stir while adding, and then stir at 100rpm for 1h after adding; (3) Cool the stirred colloidal material to room temperature, cut the colloidal material into square materials, and The block material was freeze-dried, the freeze-drying temperature was -50°C, the freeze-drying vacuum degree was 3Pa, and the freeze-drying time was 36h, and then the thoroughly dried porous material was taken out to prepare the medical hemostatic sponge material.

Embodiment 2

[0039] (1) Take an appropriate amount of water, set the water temperature to 60°C, take 15g of xanthan gum, 5g of polyethylene glycol 400, 8g of fibroin, and 12g of polyvinylpyrrolidone by weight, mix the above xanthan gum, Dissolve polyethylene glycol 400, fibroin and polyvinylpyrrolidone in water and stir at a stirring speed of 50 rpm for 30 minutes; (2) Add 3 g of triglycerol monostearate, Hydroxypropyl Distarch Phosphate 10g, stir while adding, and then stir at 50rpm for 1h after adding; (3) Cool the stirred colloidal material to room temperature, cut the colloidal material into square materials, and The block material was freeze-dried at -5°C, the freeze-drying vacuum was 500 Pa, and the freeze-drying time was 8 hours, and then the thoroughly dried porous material was taken out to prepare the medical hemostatic sponge material.

Embodiment 3

[0041] (1) Take an appropriate amount of water, set the water temperature to 60°C, take 13g of xanthan gum, 9g of polyethylene glycol 400, 4g of fibroin, and 17g of polyvinylpyrrolidone by weight, mix the above xanthan gum, Polyethylene glycol 400, fibroin and polyvinylpyrrolidone are dissolved in water and stirred at a stirring speed of 100 rpm for 30 minutes; (2) Add 5 g of triglycerol monostearate, Hydroxypropyl distarch phosphate 6g, stir while adding, and then stir at 100rpm for 1h after adding; (3) Cool the stirred colloidal material to room temperature, cut the colloidal material into square materials, and The block material was freeze-dried, the freeze-drying temperature was -30°C, the freeze-drying vacuum degree was 50Pa, and the freeze-drying time was 12h, and then the thoroughly dried porous material was taken out to prepare the medical hemostatic sponge material.

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PUM

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Abstract

The invention belongs to the field of novel medical materials, and discloses a medical hemostatic sponge material and a preparation method thereof; and the medical hemostatic sponge material comprises xanthan gum, polyethylene glycol 400, fimbrin, polyvinylpyrrolidone, tripolyglycerol monostearates and hydroxy propyl distarch phosphate. The preparation method disclosed by the invention comprises the following steps of: (1), dissolving xanthan gum, polyethylene glycol 400, fimbrin and polyvinylpyrrolidone by using a proper amount of water, and then, stirring; (2), adding tripolyglycerol monostearates and hydroxy propyl distarch phosphate and stirring; and (3), cooling to room temperature, cutting a colloid material into a square material, freezing and drying the square material, thus obtaining the medical hemostatic sponge material.

Description

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Claims

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Application Information

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Owner 美迪科(上海)包装材料有限公司
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