2 results about "Polyglycerol monostearate" patented technology

This invention belongs to the field of nanoparticle hydrogel scaffold technology, providing an MMP-responsive nanoparticle hydrogel scaffold and its application in the treatment of fibrous bone dysplasia. The nanoparticle hydrogel scaffold is prepared by cross-linking and curing triglyceride monostearate nanoparticles, 3-aminophenylboronic acid-modified hyaluronic acid, and dopamine-modified hyaluronic acid. This invention is based on the first discovery that the concentration of matrix metalloproteinases (MMPs) around fibrous bone dysplasia lesions is a biomarker reflecting the "activity and treatment response of fibrous bone dysplasia lesions," and based on this discovery, provides an MMP-responsive nanoparticle hydrogel scaffold and its application in the treatment of fibrous bone dysplasia. This nanoparticle hydrogel scaffold can achieve perilesional drug delivery and sustained MMP-responsive drug release through injection, thereby providing a local treatment strategy for fibrous bone dysplasia.

The invention discloses a low-temperature-resistant and impact-resistant polypropylene foamed sheet and a formula thereof, and relates to the technical field of foamed sheets, the low-temperature-resistant and impact-resistant polypropylene foamed sheet comprises the following raw materials: modified homo-polypropylene, modified zinc stearate, a foaming agent and a filler; according to the invention, the modified homo-polypropylene is added, so that the low-temperature impact resistance of the material can be improved, the foaming nucleation capability is optimized, the foam structure stability is improved, and the weather resistance and aging resistance of long-term low-temperature outdoor use can be remarkably enhanced; modified zinc stearate is added, the modified zinc stearate is used as a basis, polyglycerol monostearate and modified gas-phase nano silicon dioxide are used for carrying out difunctional modification to obtain a multifunctional auxiliary agent, and the multifunctional auxiliary agent can cooperate with zinc oxide to activate the ADC foaming agent and reduce the decomposition temperature of the foaming agent so as to broaden a processing temperature window; the system lubricity and melt flowability can be improved, and the problems of equipment mold sticking and material agglomeration are reduced.