An Anti-microbial dressing, an Anti-microbial composition and use thereof

Abstract

The invention relates to an antimicrobial dressing, an anti-microbial composition and use thereof. The dressing comprises: chlorhexidine and / or a pharmaceutically acceptable salt thereof in a solid state in a quantity, calculated as an equivalent weight of chlorhexidine digluconate / surface of dressing, comprised between 0.013 and 2 g / m2; and silver and / or a pharmaceutically-acceptable salt in the solid state in a quantity, calculated as an equivalent weight of metallic silver / surface of dressing of greater than or equal to 0.1 g / m2. The composition comprises: chlorhexidine and / or a pharmaceutically acceptable salt thereof in a solid state in a relative weight / weight percentage, calculated as an equivalent weight of chlorhexidine digluconate / total weight of the composition, comprised between 0.01% and 0.09%; and silver and / or a pharmaceutically acceptable salt thereof in the solid state in a relative percentage weight / weight comprised between 0.00008% and 0.08%, calculated as an equivalent weight of metallic silver / total weight of the composition; and at least a pharmaceutically-acceptable excipient.

Description

field of invention [0001] The present invention relates to the field of medical equipment, in particular to (preferably using catheters) bacteriostatic agents and bacteriostatic dressings. Background technique [0002] Patients may have areas on their skin that require dressings, such as cuts, burns, scrapes, or wounds. In these cases, sterile dressings, preferably bacteriostatic dressings, are required to prevent bacterial proliferation. This need is especially acute when catheters are physically implanted in the patient. [0003] Vascular catheters are implanted in the patient's body when it is necessary to use vascular access for direct infusion of fluids and / or administration of medicinal substances directly into a vein. This may be done for immediate access in emergency situations and for permanent vascular access in (eg, oncological conditions or peritoneal dialysis) patients. Permanent vascular access usually consists of a central venous catheter (CVC) and must be ...

AI Technical Summary

Problems solved by technology

This constitutes a disadvantage, since in order to administer prolonged and / or periodic IV therapy through the catheter, the patient must maintain an antimicrobial dressing in constant contact with the skin and change the dressing periodically

[0009] In addition, chlorhexidine and / or its salts (in solutions greater than 2% by weight) can cause conjunctivitis or severely damage the cornea

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