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A pharmaceutical composition for promoting fracture healing and its preparation method

A fracture healing and composition technology, which is applied in the field of pharmaceutical compositions for promoting fracture healing and its preparation, can solve problems such as side effects and ineffective effects, and achieve the goal of enhancing synergistic enhancement, promoting fracture healing, and good synergistic enhancement Effect

Active Publication Date: 2016-08-03
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine mainly uses pain relief and anti-inflammation methods to treat fracture swelling and promote healing, but the effect is not obvious and there are side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Take the following raw materials, in parts by weight, 120 parts of Dipsacus, 200 parts of Rhizoma Drynariae, 100 parts of Elderberry, 100 parts of Codonopsis Codonopsis, 110 parts of Radix Astragali, 120 parts of Rhizoma Chuanxiong, 150 parts of Corydalis Corydalis, 110 parts of Wood Beetle, and 5 parts of Borneol;

[0036] Prepare in the following manner:

[0037] (1) Ground beetle and borneol are crushed into subdivisions respectively, and set aside;

[0038] (2) Adopt steam distillation method to extract the volatile oil of Rhizoma Chuanxiong, the extraction time is 3h, the aqueous solution after distillation is collected with container, for subsequent use;

[0039] (3) Crush Corydalis Corydalis into coarse powder, extract according to the percolation method under (Appendix 10 of the Chinese Pharmacopoeia) fluid extract and extract, use 70% ethanol as solvent, soak for 45h, and use a speed of 1ml per minute Percolation, collecting the percolation liquid, recovering ...

Embodiment 2

[0043] Take the following raw materials, in parts by weight, 140 parts of Dipsacus, 210 parts of Rhizoma Drynariae, 130 parts of Elderberry, 135 parts of Codonopsis Codonopsis, 130 parts of Radix Astragali, 140 parts of Chuanxiong, 190 parts of Corydalis Corydalis, 120 parts of ground beetle, 7 parts of borneol;

[0044] Prepare in the following manner:

[0045] (1) Ground beetle and borneol are crushed into subdivisions respectively, and set aside;

[0046] (2) Adopt steam distillation method to extract the volatile oil of Rhizoma Chuanxiong, the extraction time is 4h, the aqueous solution after distillation is collected with container, for subsequent use;

[0047](3) Crush Corydalis Corydalis into a coarse powder, extract according to the percolation method under (Appendix 10 of Chinese Pharmacopoeia) liquid extract and extract, use 75% ethanol as solvent, soak for 48 hours, and use a speed of 2ml per minute Percolation, collecting the percolation liquid, recovering ethanol...

Embodiment 3

[0051] Take the following raw materials, in parts by weight, 160 parts of Dipsacus, 230 parts of Rhizoma Drynariae, 110 parts of Elderberry, 120 parts of Codonopsis Codonopsis, 140 parts of Radix Astragali, 160 parts of Rhizoma Chuanxiong, 170 parts of Corydalis Corydalis, 130 parts of Wood Beetle, and 9 parts of Borneol;

[0052] Prepare in the following manner:

[0053] (1) Ground beetle and borneol are crushed into subdivisions respectively, and set aside;

[0054] (2) adopt steam distillation method to extract the volatile oil of Rhizoma Chuanxiong, the extraction time is 5h, the aqueous solution after the distillation is collected with container, for subsequent use;

[0055] (3) Pulverize Corydalis Corydalis into coarse powder, extract according to the percolation method under (Appendix 10 of Chinese Pharmacopoeia) liquid extract and extract, use 80% ethanol as solvent, soak for 45h, and use a speed of 3ml per minute Percolation, collecting the percolation liquid, recove...

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Abstract

The present invention relates to the field of fracture medicine, and in particular to a pharmaceutical composition for promoting fracture healing and a preparation method thereof. The pharmaceutical composition is mainly made of the following raw materials, in terms of parts by weight, 120-180 parts of Dipsacus Dipsacus, 200-250 parts of Drynariae, 100-150 parts of Elderflower, 100-150 parts of Codonopsis pilosula, 110-150 parts of Astragalus, and Ligusticum Chuanxiong. 120-180 parts of Corydalis Corydalis, 150-200 parts of Corydalis, 110-140 parts of Scutellaria baicalensis, and 5-10 parts of Borneol. Different processing methods are used for each raw material. The active ingredients of each raw material component obtained are higher. In addition, the active ingredients of Ligusticum Chuanxiong are extracted separately. The volatile oil enables better synergistic enhancement between the active ingredients in the finally prepared medicine. The prepared pharmaceutical composition can be used in the treatment of bruises, fractures, etc., and has very good functions of activating blood circulation and removing blood stasis, connecting bones and tendons, etc. Promote fracture healing and other effects.

Description

technical field [0001] The invention relates to the field of fracture medicines, in particular to a pharmaceutical composition for promoting fracture healing and a preparation method thereof. Background technique [0002] When the integrity or continuity of the bone is disrupted, it is called a fracture. The clinical description of fractures is often named according to the cause of the trauma, the anatomical site of the trauma, the characteristics of the fracture line, and the rupture of the skin or mucous membrane, such as an open fracture of the lower end of the radius. Fractures typically require splicing, casting, and splinting to allow the bones to grow together naturally. Fractures are often accompanied by swelling of the surrounding soft tissue, which can affect venous return, resulting in limb movement impairment and pain. If not treated in time, it will cause prolonged tissue recovery time and slow growth of bone callus. [0003] After the fracture, patients will ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/66A61P19/08A61K31/045A61K35/64
CPCA61K9/0053A61K9/48A61K31/045A61K35/63A61K36/126A61K36/185A61K36/236A61K36/344A61K36/48A61K36/481A61K36/66A61K2236/333A61K2236/331A61K2236/15A61K2300/00
Inventor 吕姗珊谯志文杨超陈晓雪陈小红周年华唐桂英
Owner 重庆希尔安药业有限公司
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