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Nonwoven materials containing chlorhexidine acetate and triclosan

A non-woven material, chlorhexidine acetate technology, applied in the field of medical products, can solve the problems of increasing liquid penetration, damaging the barrier properties of non-woven materials, etc.

Inactive Publication Date: 2015-04-08
ALLEGIANCE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While the use of antimicrobial coatings on nonwovens can help reduce the number of microorganisms present on the surface, coatings can sometimes compromise the barrier properties of nonwovens, increasing the potential for liquid penetration

Method used

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  • Nonwoven materials containing chlorhexidine acetate and triclosan
  • Nonwoven materials containing chlorhexidine acetate and triclosan

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0026]Experiments were performed to compare the effect of the combination of chlorhexidine acetate (CHA) and triclosan with: (1) each of chlorhexidine free base (CH), chlorhexidine acetate, chlorhexidine gluconate alone (CHG), polyhexamethylene biguanide (PHMB) and triclosan, (2) each combination of CH and triclosan, CHG and triclosan, and PHMB and triclosan. The following coating formulations were prepared with deionized water and sprayed onto 8 x 8 inch fabric samples of 34 gsm spunbond / meltblown / spunbond (SMS) nonwovens using a disposable atomizing hand sprayer.

[0027] - Formulation A: CHA (0.6% w / w), Triclosan (0.60% w / w) and ethanol (70%)

[0028] - Formulation B: CHA (0.3% w / w), Triclosan (0.60% w / w) and ethanol (70%)

[0029] - Formulation C: CHA (0.75% w / w), Triclosan (0.60% w / w) and ethanol (70%)

[0030] - Formulation D: no coating control

[0031] - Formulation E: ethanol (70%)

[0032] - Formulation F: CH (0.30% w / w) and ethanol (70%)

[0033] - Formulation ...

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PUM

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Abstract

This invention provides medical articles having antimicrobial efficacy and good barrier properties. In particular, the medical articles comprise a nonwoven material and a coating comprising chlorhexidine acetate and triclosan.

Description

field of invention [0001] The present invention relates to medical articles having antimicrobial efficacy and excellent barrier properties. Background of the invention [0002] Hospital-acquired infections, also known as nosocomial infections, cause or contribute to nearly 100,000 deaths each year in the United States. Disposable medical articles such as gowns, drapes, shoe covers, wraps and caps are commonly used to minimize the spread of such infections. These articles are often worn or used for a short period of time, such as less than 10 minutes. [0003] Many of these articles are made of nonwoven materials or fabrics, such as spunbond / meltblown / spunbond (SMS) laminates of polypropylene fibers, and are capable of forming a barrier against microorganisms and / or liquids. The ability to impede the penetration of liquids, such as bodily fluids, is important in medical settings. Some medical articles, such as medical gowns, are classified into levels of barrier properties...

Claims

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Application Information

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IPC IPC(8): A61L31/16A61B46/00A61B90/00
CPCA61L2300/404A61B19/04A61L31/048A61L31/16A61B19/088A61L31/146A61B19/08D06M16/00A61B46/00A61B46/40C08L23/12D10B2509/00D10B2321/022
Inventor W·H·伊斯萨亚L·拉布恩-扎米伊洛K·佩特罗夫S·维格纳
Owner ALLEGIANCE CORP
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