Medicament for local anesthesia and analgesia and preparation method of medicament

A technology of local anesthesia and medicine, applied in the field of anesthesia, can solve the problems of inability to metabolize and excrete anesthesia drugs, ineffective analgesic effect, cumbersome operation methods, etc., achieve the effect of hemostasis adverse reactions, avoid adverse reactions, and easy to use

Active Publication Date: 2015-04-22
李英霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some deficiencies in the existing local anesthesia and analgesia. Some analgesic effects are not obvious, and some are prone to other side effects. Some postoperative anesthesia drugs cannot be metabolized and excreted in time. way more cumbersome

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] A medicament for local anesthesia and analgesia. The raw materials and parts by weight are as follows: Chinese medicine decoction piece component A: 0.2 parts of Xiaohei Niu, 0.8 parts of Yahonglong, 0.3 parts of Scopolamine leaves, 6 parts of white mustard seeds, 5 parts of licorice, 10 parts of Parts of water chestnut, 13 parts of big green vine, 12 parts of hemp;

[0049] Fresh product component B: 0.4 parts of red taro, 3 parts of jasmine root, 18 parts of panax notoginseng, and 7 parts of Kutianqi.

[0050] Excipients: 0.05 part of asarum volatile oil, 0.012 part of transdermal absorption accelerator, and 0.02 part of surfactant.

[0051] Wherein, the transdermal absorption enhancer is N-methyl-2-pyrrolidone, and the surfactant is polyoxyethylene sorbitan fatty acid.

[0052] The preparation method of the spray of medicament of the present invention is:

[0053] (1) Extraction of active ingredients of component A of Chinese herbal medicine: put the composition of...

Embodiment 2

[0060] A medicament for local anesthesia and analgesia. The raw materials and parts by weight are as follows: Component A of Chinese herbal medicine: 0.35 parts of Xiaohei Niu, 1.0 part of Yahonglong, 0.4 parts of Scopolamine leaves, 13 parts of white mustard seeds, 8 parts of licorice, 15 parts of Parts of water chestnut, 19 parts of big green vine, 21 parts of hexagonal hemp;

[0061] Fresh product component B: 0.5 parts of red taro, 4.5 parts of jasmine root, 25 parts of Panax notoginseng, 11 parts of Kutianqi.

[0062] Excipients: 0.10 part of Asarum volatile oil, 0.015 part of transdermal absorption accelerator, and 0.03 part of surfactant.

[0063] Wherein, the transdermal absorption enhancer is N-methyl-2-pyrrolidone, and the surfactant is polyoxyethylene sorbitan fatty acid.

[0064] The preparation method of the spray of medicament of the present invention is:

[0065] (1) Extraction of active ingredients of component A of Chinese herbal decoction pieces: put the co...

Embodiment 3

[0072] A medicament for local anesthesia and analgesia. The raw materials and parts by weight are as follows: Component A of Chinese medicine decoction pieces: 0.5 parts of Xiaohei Niu, 1.2 parts of Yahonglong, 0.5 parts of scopolamine leaves, 20 parts of white mustard seeds, 11 parts of licorice, 20 parts of Parts of horseshoe asarum, 25 parts of big green vine, 30 parts of hexagonal hemp;

[0073] Fresh product component B: 0.6 parts of red taro, 6 parts of jasmine root, 32 parts of panax notoginseng, 15 parts of kutianqi.

[0074] Excipients: 0.15 part of Asarum volatile oil, 0.018 part of transdermal absorption accelerator, and 0.04 part of surfactant.

[0075] Wherein, the transdermal absorption enhancer is N-methyl-2-pyrrolidone, and the surfactant is polyoxyethylene sorbitan fatty acid.

[0076] The preparation method of the spray of medicament of the present invention is:

[0077] (1) Extraction of active ingredients of component A of Chinese herbal medicine: put the...

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PUM

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Abstract

The invention discloses a medicament for local anesthesia and analgesia and a preparation method of the medicament. The medicament for local anesthesia and analgesia is prepared from the following raw materials in parts by weight: traditional Chinese medicine decoction piece components A: 0.2-0.5 part of aconitum bullatifolium levl, 0.8-1.2 parts of cissampelini methiodidum, 0.3-0.5 part of henbane leaves, 6-20 parts of semen brassicae, 5-11 parts of radix glycyrrhizae, 10-20 parts of asarum macranthum, 13-25 parts of tinomiscium tonkinensis and 12-30 parts of iris speculatrix; fresh components B: 0.4-0.6 part of konishii, 3-6 parts of jasmine roots, 18-32 parts of himalayan eriosema roots and 7-15 parts of himalaya nightshade. The raw materials and auxiliary materials are prepared into spray, the spray is sprayed to the surface of to-be-narcotized skin during use, convenient to use and quick in effect taking. The medicament disclosed by the invention not only can achieve the local anesthesia and analgesia effect, but also has effect on surgical hemostasis, can be used for avoiding various untoward effects after anesthesia. According to the clinical verifications, the medicament is remarkable in effect and especially suitable for local anesthesia of surgical operation.

Description

technical field [0001] The invention relates to the technical field of anesthesia, in particular to a preparation method for local anesthesia and analgesia. Background technique [0002] Anesthesia refers to the state that allows patients to undergo surgery or invasive procedures without pain and discomfort. It is generally believed that anesthesia is a kind of reversible functional inhibition of the central nervous system and (or) peripheral nervous system produced by drugs or other methods. The main feature of this inhibition is the loss of sensation, especially pain sensation. Clinically, anesthesia mainly includes general anesthesia and local anesthesia. Local anesthesia is the use of local anesthetics such as procaine, lidocaine, etc., injected into the corresponding parts to block the spinal nerves, nerve plexus or nerve trunks and thinner peripheral nerve endings, so that a certain part of the body temporarily loses feeling . The characteristic of local anesthesia ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P23/02A61P29/00
CPCA61K9/0014A61K9/12A61K36/268A61K36/285A61K36/31A61K36/48A61K36/484A61K36/59A61K36/63A61K36/81A61K36/87A61K36/88A61K36/888A61K47/22A61K47/26A61K2236/31A61K2236/331A61K2236/333A61K2236/53A61K2300/00
Inventor 李英霞郭廷山王记磊
Owner 李英霞
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