Composition with high-efficiency broad-spectrum antibacterial capacity and application of composition in cosmetics

A broad-spectrum antibacterial and composition technology, which is applied in the field of compositions with high-efficiency broad-spectrum antibacterial ability, can solve the problems of high irritation, weak antiseptic effect, and stimulating effect, and achieve high safety, good water solubility, The effect of adding a low amount

Inactive Publication Date: 2015-04-29
GUANGDONG YAWEI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The traditional preservatives suitable for cosmetics mainly include the following types, but they have been found to have more or less problems: (1) Nipagin esters, which are the most widely used and have a long history, the disadvantage is that such substances will penetrate And accumulate in human tissue to produce stimulating effect, and it has been found that such substances remain in the slices of breast cancer. Therefore, the European Union recommends banning or restricting the use of cosmetics containing paraben esters; (2) Formaldehyde and its formaldehyde release (3) Isothiazolinones, whose disadvantages are irritation and sensitization, the EU proposes to ban the use of isothiazolinone preservatives in residual cosmetics; (4) ) Organic halogen components, whose disadvantage is potential allergens; (5) Organic acids and their salts, whose disadvantages are weak antiseptic effect and strong irritation; (6) Bropol, which may generate nitrosamines, carcinogenic toxicity

Method used

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  • Composition with high-efficiency broad-spectrum antibacterial capacity and application of composition in cosmetics
  • Composition with high-efficiency broad-spectrum antibacterial capacity and application of composition in cosmetics
  • Composition with high-efficiency broad-spectrum antibacterial capacity and application of composition in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] 1. Composition formula

[0021]

[0022] 2. Preparation

[0023] Put the above components in a reaction kettle with a stirring device, stir and mix evenly, heat to 85°C, stir until completely dissolved, cool to room temperature, and obtain a 10% aqueous solution with a pH value of 3.8, light yellow to yellow transparent liquid.

[0024] 3. The minimum inhibitory concentration (MIC) of the product

[0025]

Embodiment 2

[0027] 1. Composition formula

[0028]

[0029] 2. Preparation

[0030] Put the above components in a reaction kettle with a stirring device, stir and mix evenly, heat to 80°C, stir until completely dissolved, cool to room temperature, and obtain a 10% aqueous solution with a pH value of 3.6, light yellow to yellow transparent liquid.

[0031] 3. The minimum inhibitory concentration (MIC) of the product

[0032]

Embodiment 3

[0034] 1. Composition formula

[0035]

[0036] 2. Preparation

[0037] Put the above components in a reaction kettle with a stirring device, stir and mix evenly, heat to 90°C, stir until completely dissolved, cool to room temperature, and obtain a 10% aqueous solution with a pH value of 3.7, light yellow to yellow transparent liquid.

[0038] 3. The minimum inhibitory concentration (MIC) of the product

[0039]

[0040] (2) Application examples

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PUM

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Abstract

The invention provides a composition with high-efficiency broad-spectrum antibacterial capacity. The composition is prepared by the following steps: mixing the following components in percentage by weight: 10-40 percent of hydroxyacetophenone, 5-30 percent of glycerol caprylate and 30-60 percent of C2-10 dihydric alcohol, heating to the temperature of 80-90 DEG C, completely dissolving the materials, thereby obtaining the product. According to the composition disclosed by the invention, Gram negative bacteria, gram-positive bacteria, moulds and saccharomycetes thereof in the cosmetics can be effectively inhibited and killed under the conditions of low addition amount, high safety, mildness and low irritation, and the composition has certain effects of moisturizing, assisting emulsification and resisting oxidation and is particularly suitable to serve as a preservative in the transparent system, W / O or O / W cream emulsification system and surfactant washing system. The invention also provides an application of the composition serving as a preservative in the cosmetics.

Description

technical field [0001] The invention relates to a composition, in particular to a composition with inhibitory and killing effects on bacteria and fungi, and more particularly to a composition with high-efficiency and broad-spectrum antibacterial ability. The invention also relates to the use of this composition in cosmetics. Background technique [0002] Due to the addition of a large amount of nutrients in cosmetics, it is easy to create conditions for the reproduction of microorganisms. Therefore, in the process of production, circulation and consumer use of cosmetics, microbial corruption is prone to occur. This corruption not only damages the performance of the product, but also in extreme cases. Under normal circumstances, it will also cause health hazards to users. Therefore, anti-corrosion is a topic that needs to be solved in cosmetics quality assurance. Cosmetic antiseptic methods include physical methods and chemical methods. Physical methods generally use heat st...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/37A61K8/35A61K8/34A61Q19/00A61Q19/08A01N37/02A01P1/00A01P3/00A01N35/04A01N31/02
Inventor 陈俊昭李耀品程金波
Owner GUANGDONG YAWEI BIOTECH
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