Traditional Chinese medicine soaking agent for treating chemotherapy-related peripheral nerve toxicity

Abstract

The invention discloses a traditional Chinese medicine soaking agent for treating chemotherapy-related peripheral nerve toxicity, wherein the chemotherapy-related peripheral nerve toxicity belongs to the scope of numbness, paralysis and the like in the traditional Chinese medicine, and the general symptoms are yang deficiency-cold and meridian coagulation. The traditional Chinese medicine soaking agent disclosed by the invention is prepared by selecting the traditional Chinese medicines capable of dredging meridians, regulating qi and blood, dispelling wind, eliminating dampness, warming channels, expelling cold, relaxing muscles, stimulating blood circulation, and relieving swelling and pain, such as scleria terrestris, carallia diplopetala, pellionia viridis C. H. Wright, alpinia japonica, common euscaphis fruit seeds, southern evodia fruits, ventilago leiocarpa benth, lousewort root, sopubia trifida buch, Kunming caulis spatholobi, Chinese squill and sharpspur corydalis root; through clinical tests, the total effective rate is 91%, the curative effect is remarkable, and side effects are avoided.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine soaking agent for treating chemotherapy-related peripheral neurotoxicity. Background technique [0002] Peripheral neurotoxicity is a common toxic reaction of chemotherapy drugs with a high incidence, especially vinblastine (VCR, NVB), oxalate platinum, paclitaxel, etc. Inducing peripheral neurotoxicity is one of the common toxic reactions of chemotherapy. Its mechanism has not been fully clarified, and it can occur within hours to days of medication. It can be divided into acute neurotoxicity and chronic cumulative neurotoxicity. Some drugs have been clinically validated for use in For the prevention and treatment of peripheral neurotoxicity, Western medicine mainly uses some antioxidants or cell membrane protective agents for treatment and prevention, such as growth factors, reduced glutathione, calcium, magnesium, amifostine, vitamin ...

AI Technical Summary

Problems solved by technology

Inducing peripheral neurotoxicity is one of the common toxic reactions of chemotherapy. Its mechanism has not been fully clarified, and it can occur within hours to days of medication. It can be divided into acute neurotoxicity and chronic cumulative neurotoxicity. Some drugs have been clinically proven to be used For the prevention and treatment of peripheral neurotoxicity, Western medicine mainly uses some antioxidants or cell membrane protective agents for treatment and prevention, such as growth factors, reduced glutathione, calcium, magnesium, amifostine, vitamin E, lithium, etc. Salt, etc., but the curative effect is mediocre, so many chemotherapy patients have to bear the pain and inconvenience caused by neurotoxicity

Traditional Chinese medicine mainly uses oral decoction to treat and prevent peripheral neurotoxicity, and there are few literature reports on the application of traditional Chinese medicine soaking method.