Traditional Chinese medicine effective component compound for preventing and treating fatty liver

A technology of active ingredients and fatty liver, applied in the direction of active ingredients of ketones, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of few researches and no involvement of compound prescriptions, and achieve significant prevention and control effects, safe and effective effects effect of substance

Inactive Publication Date: 2015-05-13
NINGBO NO 2 HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0021] 3. Defects or deficiencies in the process, method, performance, etc. of the existing background technology (necessity and significance of compound research on effective components of traditional Chine

Method used

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  • Traditional Chinese medicine effective component compound for preventing and treating fatty liver
  • Traditional Chinese medicine effective component compound for preventing and treating fatty liver
  • Traditional Chinese medicine effective component compound for preventing and treating fatty liver

Examples

Experimental program
Comparison scheme
Effect test

experiment approach 2

[0058] Experimental scheme 2--Validation experiment of effective component formula

[0059] 1. Model Preparation

[0060] Fatty liver model of rats with high-fat diet (induced by dietary factors alone), fed with high-fat diet (10% lard + 2% cholesterol + 88% basal feed) for 12 weeks, and the feed was produced by Shanghai Slack Experimental Animal Co., Ltd.

[0061] 2. Reagents and Drugs

[0062]Free fatty acid (FFA) enzyme-linked immunosorbent assay kit was purchased from Shanghai-based Biotechnology Co., Ltd., batch number: DRY1198-201306; triglyceride (triglyceride, TG) kit was purchased from Beijing Beihua Kangtai Clinical Reagent Co., Ltd. , batch number: 006304; total cholesterol (total cholesterol, TC) kit was purchased from Beijing Beihua Kangtai Clinical Reagent Co., Ltd., batch number: 006301. Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) kits were purchased from Nanjing Jiancheng Bioengineering Company, batch number: 20130724; salidrosid...

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PUM

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Abstract

Disclosed is a traditional Chinese medicine effective component compound for preventing and treating fatty liver. The traditional Chinese medicine effective component compound is characterized in comprising salidroside, gypenosides, curcumin and bighead atractylodes rhizome polysaccharide, wherein the ratio of each component is 4-10 parts of salidroside, 15-20 parts of gypenosides, 3-8 parts of curcumin and 65-75 parts of bighead atractylodes rhizome polysaccharide. Dosage forms of the traditional Chinese medicine effective component compound for preventing and treating fatty liver comprise tablets, capsules, pills, oral liquid or suspensions. The traditional Chinese medicine effective component compound for preventing and treating fatty liver in the invention is safe and effective, has definite active substances, and has more significant effect on preventing and treating fatty liver compared with a component compound containing a single component and Western medicine of polyene phosphatidylcholine capsule.

Description

technical field [0001] The invention relates to a medicine for preventing and treating fatty liver, in particular to a compound prescription of effective components of traditional Chinese medicine for preventing and treating fatty liver. Background technique [0002] 1. Basic overview of existing product technology: [0003] (1) Epidemiology, pathogenesis and current status of Western medicine treatment of non-alcoholic fatty liver [0004] Nonalcoholic fatty liver disease (NAFLD) refers to a clinicopathological syndrome characterized by diffuse bullous steatosis in hepatocytes, which is caused by alcohol and other definite liver damage factors. In recent years, as the pathological manifestation of metabolic diseases in the liver, it has become the target of close clinical monitoring and research, and its related disease spectrum includes simple fatty liver (simple fatty liver, SFL), steatohepatitis (Nonalcoholic steatohepatitis, NASH) , liver cirrhosis and even hepatocell...

Claims

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Application Information

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IPC IPC(8): A61K36/424A23L1/29A61P1/16A61K31/12A61K31/715A61K31/7032A23L33/00
Inventor 李红山
Owner NINGBO NO 2 HOSPITAL
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