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Soft capsule for treating psoriasis and preparation method thereof

A soft capsule and a technology for psoriasis are applied in the field of soft capsules for treating psoriasis and their preparation, and can solve the problems of incomplete radical cure, inconvenient medication, repeated attacks and the like

Inactive Publication Date: 2015-06-10
高旭
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of psoriasis mostly uses external medicine, which is inconvenient to use, incomplete cure, and repeated attacks

Method used

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  • Soft capsule for treating psoriasis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1, a, 130 grams of Sanchaku, 170 grams of yellow quail, 220 grams of Mishuige, 190 grams of Cistanche, 260 grams of Commelina, 280 grams of Polygonum multiflorum, 180 grams of oregano, 140 grams of Radix Ophiopogon, 210 grams of Rhizoma Chuanxiong Mix and pulverize 1 g, add 85% ethanol according to the ratio of material to liquid 1:9, reflux extraction 3 times, each time for 2 hours, combine the reflux liquid; concentrate into an extract with a relative density of 1.28-1.32 (35°C);

[0023] b. Dry the extract in step a to make 400 mesh powder, mix evenly with 50 grams of grape seed oil, pack into soft capsules according to 0.56 grams per capsule.

Embodiment 2

[0024] Example 2, a, 120 grams of Sanchaku, 160 grams of yellow quail, 200 grams of Mishuige, 180 grams of Cistanche, 250 grams of Commelina, 270 grams of Polygonum multiflorum, 170 grams of oregano, 120 grams of Radix Ophiopogon, 210 grams of Rhizoma Chuanxiong Mix and pulverize 1 g, add 85% ethanol according to the ratio of material to liquid 1:9, reflux extraction 3 times, each time for 2 hours, combine the reflux liquid; concentrate into an extract with a relative density of 1.28-1.32 (35°C);

[0025] b. Dry the extract in step a to make 400 mesh powder, mix evenly with 40 grams of grape seed oil, pack into soft capsules according to 0.56 grams per capsule.

Embodiment 3

[0026] Example 3, a, 150 grams of Sanchaku, 180 grams of yellow quail, 230 grams of Mishuige, 200 grams of Cistanche, 270 grams of Commelina, 290 grams of Polygonum multiflorum, 190 grams of oregano, 150 grams of Radix Ophiopogon, 230 grams of Rhizoma Chuanxiong Mix and pulverize 1 g, add 85% ethanol according to the ratio of material to liquid 1:9, reflux extraction 3 times, each time for 2 hours, combine the reflux liquid; concentrate into an extract with a relative density of 1.28-1.32 (35°C);

[0027] b. Dry the extract in step a to make 400 mesh powder, mix evenly with 50 grams of grape seed oil, pack into soft capsules according to 0.56 grams per capsule.

[0028] The relevant clinical data are as follows: General data: 279 patients with psoriasis vulgaris. Among them, there were 178 males and 101 females, aged from 19 to 54 years old, with an average age of 36.8 years, and the course of disease was 2 months to 6 years, with an average of 3.22 years. They were randomly ...

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Abstract

The invention provides a preparation method for a soft capsule for treating psoriasis. The method includes the following steps that firstly, by weight, parts of evodia lepta, youngia japonica, sri lanka pouzolzia herb, desertliving cistanche, dayflowers, polygonum multiflorum, majoram, radix ophiopogonis and ligusticum wallichii are mixed and ground, 85% ethyl alcohol is added to a mixture according to the material to liquid ratio of 1:9, reflux extraction is conducted three times and lasts for two hours each time, and reflux liquid is combined; the liquid is concentrated into concentrate with the relative density ranging from 1.28 to 1.32 at the temperature of 25 DEG C; secondly, the concentrate in the first step is dried to make powder of 400 meshes, the powder is evenly mixed with grape seed oil of the corresponding parts of weight, and the mixture is placed into the capsule. According to the capsule, the synergistic effect of medicine ingredients is obvious, the effect which can not be achieved by single medicine or a combination of a plurality of kinds of medicine is achieved on treating psoriasis, and the soft capsule has the effects of nourishing yin, generating saliva, invigorating the circulation of blood and qi, tonifying essence and blood, achieving detoxification, eliminating carbuncle, resisting bacteria and diminishing inflammation and is remarkable in psoriasis treatment effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a soft capsule for treating psoriasis and a preparation method thereof. Background technique [0002] Psoriasis, commonly known as "psoriasis", is a common chronic inflammatory skin disease that is prone to recurrence. The characteristic damage is red papules or plaques covered with multiple layers of silvery white scales. The incidence is the most in young adults, more in men than in women, more in the north than in the south, prone to or aggravated in spring and winter, and relieved in summer and autumn. The etiology and pathogenesis are not completely clear, the study found that the incidence of the disease is related to genetic factors, streptococcus infection, abnormal immune function, metabolic disorders and endocrine changes. [0003] Psoriasis is a common chronic inflammatory skin disease. It is a disease of polygenic inheritance, which can be induced...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/48A61P17/06
Inventor 高旭
Owner 高旭
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